Results 141 to 150 of about 241,000 (259)

Plongée dans les archives pie XII

open access: yes, 2020
Une interview de Nina Valbousquet pour le programme Babel de la Radio Télévision Suisse (RTS) : Après quelques péripéties liées au Covid-19, lʹexploration des archives du pontificat de Pie XII (1939 - 1958) a commencé.
Marie Levant
core  

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

open access: yesAdvanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero   +3 more
wiley   +1 more source

Pie diabético y su relación con la hemoglobina glicosilada en pacientes con diabetes mellitus tipo 2 en el Centro de Salud número 1 de la ciudad de Ibarra, provincia de Imbabura, de septiembre a noviembre del 2016

open access: yes, 2016
La Diabetes Mellitus Tipo 2 es una enfermedad crónica relevante no solo por encontrarse dentro de las primeras causas de morbimortalidad sino también por las complicaciones micro y macrovasculares que presenta el paciente asociado a la hiperglicemia, al ...
Quelal Narváez, Rosa Liliana   +1 more
core   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

open access: yesAdvanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng   +12 more
wiley   +1 more source

Stretchable, Self-Healing, and Processable Bioelastomers Enabled by Highly Branched Cross-Linking Networks for Flexible Electronics. [PDF]

open access: yesResearch (Wash D C)
Liu Y   +15 more
europepmc   +1 more source

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

open access: yesAdvanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang   +8 more
wiley   +1 more source

A physics-informed eikonal model for simulating arrhythmias in the human heart in real-time. [PDF]

open access: yesNat Commun
Schrotter TG   +6 more
europepmc   +1 more source

Pie eating at 4H club fair.

open access: yes
The 4-H Club fair. End of the pie eating contest; winner has his hand raised.

core  

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