Results 121 to 130 of about 241,000 (259)
La Santa Lucia Filippini : fondatrice e superiora del Istituto delle Maestre Pie Filippini
, 1930 Ante
Salotti, Carlos
core
Advanced Science, EarlyView.A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu +7 more
wiley +1 more source
Braquimetatarsia: Revisión de la literatura a propósito de dos casos. Informe de casos
Salud UIS, 2015 La braquimetatarsia es una enfermedad en el pie, considerada rara, definida como el acortamiento anormal del metatarsiano. Su incidencia en la población está en el rango de 0.02- 0.05%, y predomina en el sexo femenino (25:1).
Diego F Rincón C +3 more
doaj
Advanced Science, EarlyView.Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen +14 more
wiley +1 more source
La beata Lucia Filippini : fondatrice e Superiora dell'Istituto delle Maestre Pie Filippini
, 1926 Marca tip. na portData de prelim., 1926Lám. en b. e n.
Salotti, Carlos
core
Prevalencia de pie plano en niños del Valle de los Chillos; sector San Rafael, cantón Quito, provincia de Pichicha en el período diciembre 2010 - enero 2011 [PDF]
, 2011 Se trata de un estudio epidemiológico de tipo transversal, cuyo principal objetivo fue determinar la prevalencia de pie plano en los niños de tres a diez años de edad, de las escuelas públicas y privadas del Valle de los Chillos durante el periodo ...
León Ripalda, Juan Francisco
core
Aggregation‐Controlled Triplet Exciton Regulation Enables Single‐Emitter Color‐Evolving Afterglow
Advanced Science, EarlyView.A single‐emitter system based on DTP‐R luminophores enables time‐evolving afterglow through aggregation‐regulated excited‐state dynamics. The coexistence and suppression of delayed fluorescence and phosphorescence are controlled via concentration tuning and host‐guest engineering, revealing the RISC origin of delayed fluorescence and enabling ...
Yu Zhang +14 more
wiley +1 more source
Advanced Science, EarlyView.IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia +8 more
wiley +1 more source
Advanced Science, EarlyView.Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li +11 more
wiley +1 more source
Scalable Routing Easy as PIE: a Practical Isometric Embedding Protocol (Technical Report) [PDF]
We present PIE, a scalable routing scheme that achieves 100% packet delivery and low path stretch. It is easy to implement in a distributed fashion and works well when costs are associated to links. Scalability is achieved by using virtual coordinates in
Herzen, Julien +2 more
core +1 more source