Results 161 to 170 of about 11,131 (244)

WNK1 Kinase Activity Is Required for the Functional Maintenance of Podocyte Structure

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
The acute effects of WNK1 kinase inhibition on podocyte structure and function were determined at the level of: 1) renal function, by measurements of urinary protein and imaging of glomerular synaptopodin, 2) podocyte cell, by measurements and localization of actomyosin proteins and their regulators, and 3) focal adhesions at cell membrane extensions ...
Zhenan Liu, Eunyoung Lee, Shumeng Jiang, Joonho Yoon, Fouzia Ahmed, Mohammad A. Rahman, Philip Bleicher, Hani Y. Suleiman, Leslie A. Bruggeman, R. Tyler Miller, Audrey N. Chang   +10 more
wiley   +1 more source

Piezo1 overexpression in the uterus contributes to myometrium contraction and inflammation-associated preterm birth

Journal of Translational Medicine
Background Preterm birth, a leading cause of perinatal mortality and morbidity, is often associated with inflammation and aberrant myometrial contractions.
Yanmei Bi, Hao Li, Min Diao, Qian Liu, Lu Huang, Yunkai Tao, Yantong Wan, Xuemei Lin   +7 more
doaj   +1 more source

Pressure‐sensing Piezo1: the eyes have it [PDF]

The Journal of Physiology, 2020
Sandip M. Swain, Rodger A. Liddle
openaire   +2 more sources

The role of Piezo1 in immune cells and pregnancy. [PDF]

Front Immunol
Fei Y, Liu Y, Zhang L.
europepmc   +1 more source

Etiology, diagnosis and treatment of lumbar disc degeneration: a focus on the mechanism of action of Piezo1 and research perspectives. [PDF]

Front Cell Dev Biol
Gong Y, Cheng Z, He J, Gan Y, Jiang X, Liu J.   +5 more
europepmc   +1 more source

The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA signaling. [PDF]

Sci Rep
Hägg D, Li L, Beeve AT, Scheller EL, Bellman J, Anesten F, Zlatkovic J, Dalmau Gasull A, Font-Gironès F, Movérare-Skrtic S, Jansson JO, Ohlsson C.   +11 more
europepmc   +1 more source

Compressive stress-driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory. [PDF]

Sci Adv
Boyle ST, Gallego-Ortega D, Buckley EJ, Cognard E, Johan MZ, Esmaeili Z, Kamei M, Poole K, Samuel MS.   +8 more
europepmc   +1 more source

PIEZO Force Sensors and the Heart. [PDF]

Cold Spring Harb Perspect Biol
McGrane A, Murray M, Bartoli F, Giannoudi M, Conning-Rowland M, Stewart L, Levelt E, Cubbon RM, Dall'Armellina E, Griffin KJ, Herum KM, Smith AJ, Beech DJ.   +12 more
europepmc   +1 more source

Deciphering gain-of-function from loss-of-function variants with AlphaMissense: A case study with the mechanosensitive PIEZO1 ion channel protein. [PDF]

Biochem Biophys Rep
Pillai J, Sridhar A, Sung K, Shi L, Wu C.   +4 more
europepmc   +1 more source

Piezo1 as a mechanical checkpoint in T cell immunotherapy for solid tumors. [PDF]

Front Pharmacol
Cui X, Zhao J, Tian H.
europepmc   +1 more source