Results 181 to 190 of about 10,071 (256)

The role of ECM-PIEZO1-axis-mediated mechanosensation in the central nervous system. [PDF]

Front Neurol
Zhang X, Zhu Y, Song S, Liu P, Liu C, Li H, Zhang Y, Wang C, Du M, Tang D, Hu Y.   +10 more
europepmc   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, Volume 59, Issue 9, September 2026.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Piezo1 drives fibroblast activation in epidural fibrotic remodelling via the ET-1/HIF-1α pathway. [PDF]

Bone Joint Res
Huang Y, Song Z, Mei X, Zhao Y, Zhu T, Shi M, Sun J, Zhang M, Wu T, Liu J.   +9 more
europepmc   +1 more source

Future Prospects of Ultrasound: Role of Low‐Intensity Transcranial Ultrasound Stimulation in the Treatment of Neurological and Psychiatric Disorders

European Journal of Neurology, Volume 33, Issue 9, September 2026.
ABSTRACT Background Neurological and psychiatric disorders pose a persistent global health burden, with conventional therapies often providing inadequate relief. Transcranial ultrasound stimulation (TUS) has attracted considerable attention as a non‐invasive neuromodulation technique offering high spatial resolution and the distinctive capacity to ...
Yunjie Sui, Mingyue Wei, Robert Chen, Xue Xia   +3 more
wiley   +1 more source

Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT‐qPCR Validation

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Step I: Screened HR/SMYD4 as key keloid epigenetic genes via bulk/scRNA‐seq and machine learning. Step II: Built a high‐performance nomogram (AUC = 0.988). Step III: Conducted multi‐omics analyses. Step IV: Experimentally verified their differential expression and pathogenic roles.
Yifei Wang, Shuqian Dou, Mingkun Dai, Guoxun Yang, Wenjun Liu   +4 more
wiley   +1 more source

The mechano-immunological barrier in fibrosis-associated lung cancer: targeting matrix stiffness and the Piezo1 axis for microenvironment normalization. [PDF]

Front Pharmacol
Guo L, Wang J, Ni B, Jiang J.
europepmc   +1 more source

Inhibiting the Endothelial Mechanosensitive Channel Piezo1 Restores Hippocampal Blood-Brain Barrier Integrity to Improve Anesthesia- and Surgery-Induced Cognitive Decline. [PDF]

MedComm (2020)
Qiu Y, Mo C, Wu J, Li J, Xu S, Chen L, Zhang L, Huang X, Zhang Y, Sun M, Kang Y, Zhu T, Ding BS, Chen G.   +13 more
europepmc   +1 more source

Piezo1: Molecular mechanisms and therapeutic potential in ligamentum flavum hypertrophy and lumbar spinal stenosis. [PDF]

Redox Biol
Chen X, Yang S, Zhu C, Yu X, Wang Y, Tian Y, Liu T, Wang S.   +7 more
europepmc   +1 more source

Inflammation-Associated Changes in Piezo1 Expression, Mitophagy-Related Markers, and Matrix Dysregulation in an LPS-Stimulated Co-Culture Organoid System. [PDF]

Cells
Raja K, Suresh DG, Albeshri JK, Rawat SS, Prithishkumar IJ, Nau T, Naidoo N.   +6 more
europepmc   +1 more source

Piezo channels in physical field therapy: From mechanotransduction mechanisms to bioelectromagnetic modulation and biomedical applications. [PDF]

Mechanobiol Med
Li B, Kang HM, Pan WD, Li Y.
europepmc   +1 more source