Results 191 to 200 of about 11,131 (244)

Mechanoresponsive ion channels Piezo1 and TRPV4 stimulate ADAM10 and ADAM17 with differential impact on endothelial migration and proliferation. [PDF]

Cell Commun Signal
Pabst A, Brock N, Hardt S, Grannemann CCF, Kubiza H, Thiebes AL, Ludwig A, Babendreyer A.   +7 more
europepmc   +1 more source

Stiff matrix drives microglial cell migration through Piezo1/Ca²⁺/AKT/cofilin signaling axis-regulated F-actin reassembly. [PDF]

Regen Biomater
Chen X, Li Z, Men J, Shao H, Bai J, Guo Y, Chen X, Fan Y, Jiang LH, Jia X.   +9 more
europepmc   +1 more source

Physiology and pharmacology Piezo1 channels

Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2018
openaire   +2 more sources

PIP₂ corrects an endothelial Piezo1 channelopathy. [PDF]

Proc Natl Acad Sci U S A
Hashad AM, Abd-Alhaseeb MM, Lim XR, Mathieu NM, Harraz OF.   +4 more
europepmc   +1 more source

Piezo-type mechanosensitive ion channel component 1: a mechano-bioenergetic transducer in the tumour microenvironment. [PDF]

Ann Med
Zhang Y, Gao C, Li Y, Fu Q, Liu Y, Mo N, Yue J, Wang Y.   +7 more
europepmc   +1 more source

Abnormal mechanical load aggravates subchondral bone remodeling and uneven tibial plateau settlement in knee osteoarthritis via activation of osteoblast Piezo1-Ca²⁺-JAK2/STAT3 signaling. [PDF]

Int J Biol Sci
Li H, Zhang S, Feng C, Cheng F, Han Y, Wang M, Zhou S, Shao W, Chen W, Chen J, Liu K, Zhang Y, Wang J.   +12 more
europepmc   +1 more source

Effects of the Dental Implant Surface Topography and Macrophage Polarisation on Osteogenesis and Angiogenesis. [PDF]

Int Dent J
Liu B, Du Y, Wang M, Zhang Z, Yin W, Hu Y, Yang F.   +6 more
europepmc   +1 more source

Piezo1-driven mechanotransduction regulates mitochondrial biogenesis by AMPK/SIRT1-mediated PGC-1α deacetylation to ameliorate bone loss in disuse osteoporosis. [PDF]

Int J Biol Sci
Chen J, Wu D, Huang C, Yan Z, Wang J, Li S, Chen X, Zhu Y, Zhang Y.   +8 more
europepmc   +1 more source

<i>ALDH2 rs671</i> Variant Lowers Blood Pressure Via the Endothelial HSPA5-PIEZO1-eNOS Pathway. [PDF]

J Am Heart Assoc
Ye H, Yue H, Wei S, Wang K, Yang K, Du H, Sang W, Guo J, Wang J, Guo Y, Zhang C, Cui S, Xu F, Chen Y.   +13 more
europepmc   +1 more source