Results 101 to 110 of about 44,836 (257)

H19/Igf2 methylation statuses in piglets.

, 2015
A, cloned piglets without or with macroglossia, B and C, methylation statuses of H19/Igf2 in cloned piglets. IVF, the IVF piglets, NT-CON-N, normal cloned piglets in the NT-CON group, NT-CON-M, cloned piglets with macroglossia in the NT-CON group, and NT-
Yanjun Huan (220372), Yanshuang Mu (371081), Qingran Kong (220382), Jiang Zhu (40858), Bo Huang (30906), Zhonghua Liu (148625)   +5 more
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Relative Igf2 transcripts in fetuses and piglets.

, 2015
A, Igf2 transcripts in fetuses, and B, Igf2 expression levels in piglets. IV, the in vivo produced fetuses or piglets, IV-D, the in vivo produced dead piglets, IVF, the IVF fetuses or piglets, NT-CON-N, the normal cloned fetuses or piglets in the NT-CON ...
Yanjun Huan (220372), Yanshuang Mu (371081), Qingran Kong (220382), Jiang Zhu (40858), Bo Huang (30906), Zhonghua Liu (148625)   +5 more
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Classification of Sows for Longevity Based on Total Number of Piglets Born Alive in the First Parities [PDF]

Brazilian Archives of Biology and Technology
The aim of this study was to classify the sows for longevity based on the total number of piglets born alive in the first parities. Data comprising the period from January 2017 to March 2020 were obtained from a commercial farm with 5,500 sows.
João Otávio Hilgemberg, Ines Andretta, Alexandre Bonadiman Mariani, Alisson Neimaier, Marcio Valk, Guilherme Beber Jasluk, Fernando Bittarello, Cheila Roberta Lehnen   +7 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Comparison of fecal microbial diversity between meishan piglets with or without diarrhea

Siliao yanjiu, 2021
The experiment studied the effect of comparison of fecal microbial diversity and species structure composition of healthy and diarrhea meishan piglets. 54 fecal samples of healthy and 12 diarrhea Meishan piglets were selected for 16S rDNA sequencing to ...
Li XU, Ying LIU, Jiang ZHANG, Yong-xia ZHANG, Hui-nan JIANG, Shu-ling DAI   +5 more
doaj  

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Impact of a Phytogenic Feed Additive on Diarrhea Incidence, Intestinal Histomorphology and Fecal Excretion of F4-Fimbriated Enterotoxigenic Escherichia coli in Post-Weaning Piglets

Stresses
This study investigated the effects of a phytogenic feed additive (PFA) containing a blend of herbs, plant extracts and essential oils from the Lamiaceae, Schisandraceae, Zingiberaceae and Fabaceae families on the fecal score, intestinal histomorphology ...
Torres-Pitarch Alberto, Anja Keiner, Maud Le Gall, Francesc Molist, Xiaonan Guan, Anouschka Middelkoop, Encarnación Jiménez-Moreno, Aitor Balfagón, Graziano Mantovani, Miquel Nofrarías, Tobias Aumiller   +10 more
doaj   +1 more source