Results 111 to 120 of about 82,520 (304)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Classification of Sows for Longevity Based on Total Number of Piglets Born Alive in the First Parities [PDF]

Brazilian Archives of Biology and Technology
The aim of this study was to classify the sows for longevity based on the total number of piglets born alive in the first parities. Data comprising the period from January 2017 to March 2020 were obtained from a commercial farm with 5,500 sows.
João Otávio Hilgemberg, Ines Andretta, Alexandre Bonadiman Mariani, Alisson Neimaier, Marcio Valk, Guilherme Beber Jasluk, Fernando Bittarello, Cheila Roberta Lehnen   +7 more
doaj   +1 more source

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Advanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Luis M. Arellano, Tommaso Battisti, Gloria Garcia‐Ortega, Neus Lozano, Alberto Bianco, Kostas Kostarelos, Laura Ballerini, Giada Cellot   +10 more
wiley   +1 more source

Talking tails : quantifying the development of tail biting in pigs [PDF]

, 2010
Tail biting is an adverse behaviour characterised by manipulation of a pig’s tail by another pig resulting in tail damage and a possible tail biting outbreak. Tail biting is a common problem in the pig husbandry causing economic losses and reduced animal
Zonderland, J.J.
core  

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Impact of a Phytogenic Feed Additive on Diarrhea Incidence, Intestinal Histomorphology and Fecal Excretion of F4-Fimbriated Enterotoxigenic Escherichia coli in Post-Weaning Piglets

Stresses
This study investigated the effects of a phytogenic feed additive (PFA) containing a blend of herbs, plant extracts and essential oils from the Lamiaceae, Schisandraceae, Zingiberaceae and Fabaceae families on the fecal score, intestinal histomorphology ...
Torres-Pitarch Alberto, Anja Keiner, Maud Le Gall, Francesc Molist, Xiaonan Guan, Anouschka Middelkoop, Encarnación Jiménez-Moreno, Aitor Balfagón, Graziano Mantovani, Miquel Nofrarías, Tobias Aumiller   +10 more
doaj   +1 more source

Comparison of fecal microbial diversity between meishan piglets with or without diarrhea

Siliao yanjiu, 2021
The experiment studied the effect of comparison of fecal microbial diversity and species structure composition of healthy and diarrhea meishan piglets. 54 fecal samples of healthy and 12 diarrhea Meishan piglets were selected for 16S rDNA sequencing to ...
Li XU, Ying LIU, Jiang ZHANG, Yong-xia ZHANG, Hui-nan JIANG, Shu-ling DAI   +5 more
doaj  

Addition of oat hulls to an extruded rice-based diet for weaner pigs ameliorates the incidence of diarrhoea and reduces indices of protein fermentation in the gastrointestinal tract [PDF]

, 2008
An experiment was conducted to determine whether adding oat hulls to weaner pig diets based on extruded rice or unprocessed wheat influenced post-weaning diarrhoea (PWD) and protein fermentation in the large intestine.
Pluske, J.R., Mullan, B.P., Hampson, D.J., Kim, J.C.   +3 more
core  

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source