Results 171 to 180 of about 4,669,551 (309)

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho   +27 more
wiley   +1 more source

Pigmented spindle cell nevus.

open access: yesNishi Nihon Hifuka, 1987
URABE, Atsumichi   +2 more
openaire   +1 more source

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund   +7 more
wiley   +1 more source

Putative mechanisms of ocular inflammation in syphilis. [PDF]

open access: yesJ Ophthalmic Inflamm Infect
Ashander LM   +5 more
europepmc   +1 more source

The dermoscopy of pigmented basal cell carcinoma

open access: yesJournal of Cutaneous and Aesthetic Surgery, 2020
Kinnera, Boina   +2 more
openaire   +2 more sources

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud   +3 more
wiley   +1 more source

Chrysin attenuates diabetes‐induced retinal injury by inhibiting microglial GBP3/NLRP3/GSDMD‐mediated pyroptosis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu   +9 more
wiley   +1 more source

In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice

open access: yesAdvanced NanoBiomed Research, EarlyView.
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin   +22 more
wiley   +1 more source

Annatto‐Derived Carotenoids (Bixin and Norbixin) As Biodiesel Antioxidants: Characterization and Effects on Oxidative Stability (Rancimat and PetroOXY)

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
Annatto‐derived bixin and norbixin were characterized and evaluated as natural antioxidants for soybean biodiesel. Their antioxidant performance and effects on oxidative stability were assessed using DPPH, Rancimat, and PetroOXY methods. ABSTRACT The increasing use of eco‐friendly fuels is increasing the production of biodiesel but soybean biodiesel is
Marco Aurélio da Silva Coutinho   +4 more
wiley   +1 more source

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