Results 171 to 180 of about 4,669,551 (309)
Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho +27 more
wiley +1 more source
A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund +7 more
wiley +1 more source
Putative mechanisms of ocular inflammation in syphilis. [PDF]
Ashander LM +5 more
europepmc +1 more source
The dermoscopy of pigmented basal cell carcinoma
Kinnera, Boina +2 more
openaire +2 more sources
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud +3 more
wiley +1 more source
We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu +9 more
wiley +1 more source
Microbial production of eumelanin from a desert-derived Aspergillus terreus: statistical optimization, comprehensive characterization, and in silico insights into breast cancer-associated targets. [PDF]
El-Sapagh S +4 more
europepmc +1 more source
In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice
Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin +22 more
wiley +1 more source
Annatto‐derived bixin and norbixin were characterized and evaluated as natural antioxidants for soybean biodiesel. Their antioxidant performance and effects on oxidative stability were assessed using DPPH, Rancimat, and PetroOXY methods. ABSTRACT The increasing use of eco‐friendly fuels is increasing the production of biodiesel but soybean biodiesel is
Marco Aurélio da Silva Coutinho +4 more
wiley +1 more source

