Results 111 to 120 of about 2,749,048 (351)

Primary Cell Cultures from the Mouse Retinal Pigment Epithelium.

Journal of Visualized Experiments, 2018
The retinal pigment epithelium (RPE) is a highly polarized multi-functional epithelium that is located between the neural retina and the choroid of the eye.
P. Shang, N. Stepicheva, S. Hose, J. Zigler, D. Sinha   +4 more
semanticscholar   +1 more source

Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration

Cell Reports, 2020
Summary: Age-related macular degeneration (AMD) is a leading cause of vision loss. To better understand disease pathogenesis and identify causal genes in GWAS loci for AMD risk, we present a comprehensive database of human retina and retinal pigment ...
Luz D. Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J. Katschke, Jr., Rommel Arceo, Carmina Espiritu, Patrick Caplazi, Sarajane Saturnio Nghiem, Ying-Jiun Chen, Zora Modrusan, Amy Dressen, Leonard D. Goldstein, Christine Clarke, Tushar Bhangale, Brian Yaspan, Marion Jeanne, Michael J. Townsend, Menno van Lookeren Campagne, Jason A. Hackney   +18 more
doaj  

Idiopathic pigmented vitreous cyst without autofluorescence: a case report

BMC Ophthalmology, 2017
Background Vitreous cysts are rare clinical findings and seldom cause visual disturbance. They are generally classified as congenital or acquired and are considered idiopathic when the etiology can not be determined.
Jing Lu, Yan Luo, Lin Lu
doaj   +1 more source

Near-infrared transillumination imaging combined with aperture photometry for the quantification of melanin in the iris pigment epithelium.

PLoS ONE, 2020
Near-infrared transillumination is used in the diagnosis and the management of different eye diseases. In particular, it enables the visualization of melanin in the pigment epithelium of the iris.
Maciej Czepita
doaj   +1 more source

A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. [PDF]

PLoS Genetics, 2012
The separation of the optic neuroepithelium into future retina and retinal pigment epithelium (RPE) is a critical event in early eye development in vertebrates.
Kapil Bharti, Melanie Gasper, Jingxing Ou, Martha Brucato, Katharina Clore-Gronenborn, James Pickel, Heinz Arnheiter   +6 more
doaj   +1 more source

Autologous full-thickness RPE-choroid graft to treat high-risk drusenoid pigment epithelial detachment without CNV

GMS Ophthalmology Cases, 2020
Objective: To report on the survival of a retinal pigment epithelium (RPE)-choroid graft translocated to treat a patient with drusenoid pigment epithelial detachment (DPED).Methods: We describe a patient with bilateral high-risk DPED where one eye was ...
Sillen, Hedwig, Ruys, Joke, Schauwvlieghe, Pieter-Paul, Veckeneer, Marc   +3 more
doaj   +1 more source

Histochemical indications for a chemically complex signal produced by the cervical gill slit gland of the pygmy sperm whale (Kogia breviceps)

The Anatomical Record, EarlyView.
Abstract The pygmy sperm whale (Kogia breviceps) possesses an exocrine gland associated with its false gill slit pigmentation pattern. The cervical gill slit gland is a compound tubuloalveolar gland that produces a holocrine secretion and displays maturational changes in size and secretory histology. While the morphology of the cervical gill slit gland
Tiffany F. Keenan, William A. McLellan, Sentiel A. Rommel, Alexander M. Costidis, Craig A. Harms, J. G. M. Thewissen, Susan J. Rehorek, David S. Rotstein, Mark D. Gay, Alison R. Taylor, Heather N. Koopman, Ying Wang, Stephanie Kamel, D. Ann Pabst   +13 more
wiley   +1 more source

Quantitative phase imaging of retinal cells [PDF]

arXiv, 2017
The health of cells found in the inner retinal layers of the human eye is crucial to understand the onset of diseases of the retina such as macular degeneration and retinopathy. A challenge is to periodically image these cells in human eyes to detect abnormalities well before physiological and pathological changes occur.
arxiv  

Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill

BMC Neuroscience, 2004
Background In fish, melanin pigment granules in the retinal pigment epithelium disperse into apical projections as part of the suite of responses the eye makes to bright light conditions.
Crittenden Elizabeth L, González Alfredo, García Dana M   +2 more
doaj   +1 more source

Cryopreservation practices in clinical and preclinical iPSC‐based cell therapies: Current challenges and future directions

Biotechnology Progress, EarlyView.
Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin, Geoffrey Toner, Ronald Kander   +2 more
wiley   +1 more source