Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance
Journal of Biophotonics, EarlyView.This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy +5 more
wiley +1 more source
DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images [PDF]
arXiv, 2019 Purpose: To remove retinal shadows from optical coherence tomography (OCT) images of the optic nerve head(ONH). Methods:2328 OCT images acquired through the center of the ONH using a Spectralis OCT machine for both eyes of 13 subjects were used to train a generative adversarial network (GAN) using a custom loss function.
arxiv
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
Journal of Biophotonics, EarlyView.ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab +4 more
wiley +1 more source
Noninvasive identification of carbon-based black pigments with pump-probe microscopy [PDF]
Carbon-based black pigments, a widely used class of pigments, are difficult to differentiate with the noninvasive techniques currently used in cultural heritage science. We utilize pump-probe microscopy to distinguish four common carbon-based black pigments as pure pigments, as two-component black pigment mixtures, and as a mixture of a black and a ...
arxiv +1 more source
Valsalva-Related Subretinal Hemorrhage as a Presenting Symptom of Polypoidal Choroidal Vasculopathy
Case Reports in Ophthalmological Medicine, 2017 Purpose. To describe a case of Valsalva-related subretinal hemorrhage as a presenting symptom of polypoidal choroidal vasculopathy (PCV). The patient refrained from treatment against our best advice, and thus this is also a rare case of the natural ...
Yousif Subhi, Torben L. Sørensen
doaj +1 more source
Knowledge infused cascade convolutional neural network for segmenting retinal vessels in volumetric optical coherence tomography [PDF]
arXiv, 2019 We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal vessels locate between the inner limiting membrane and the inner nuclear layer of human retina. (2) Imaging.
arxiv
U-Net with spatial pyramid pooling for drusen segmentation in optical coherence tomography [PDF]
arXiv, 2019 The presence of drusen is the main hallmark of early/intermediate age-related macular degeneration (AMD). Therefore, automated drusen segmentation is an important step in image-guided management of AMD. There are two common approaches to drusen segmentation. In the first, the drusen are segmented directly as a binary classification task.
arxiv
Optic Disc Pallor in Parkinson's Disease: A UK Biobank Study
Movement Disorders, EarlyView.Abstract Background Recent studies have suggested that retinal changes measured with optical coherence tomography are detectable in early Parkinson's disease (PD), highlighting the potential of ophthalmic biomarkers for diagnosis and monitoring. Objective We set out to investigate the relationship between optic disc pallor measured in fundoscopy images
Samuel Gibbon +3 more
wiley +1 more source
Multiclass segmentation as multitask learning for drusen segmentation in retinal optical coherence tomography [PDF]
arXiv, 2019 Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom anatomical interfaces that define drusen, the outer boundary of the retinal pigment epithelium (OBRPE) and the Bruch's ...
arxiv
Deep Learning-Enhanced Robotic Subretinal Injection with Real-Time Retinal Motion Compensation [PDF]
arXivSubretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as age-related macular degeneration (AMD). However, retinal motion caused by physiological factors such as respiration and heartbeat significantly impacts precise needle positioning, increasing the risk of retinal pigment epithelium (RPE ...
arxiv