Comparison of choroidal hypertransmission and retinal pigment epithelium loss for quantification of geographic atrophy across commonly used SD-OCT devices. [PDF]
Eidenberger A +6 more
europepmc +1 more source
Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Monitoring Acute Posterior Multifocal Placoid Pigment Epitheliopathy Disease Progression Using Non-invasive Multimodal Imaging: A Case Series. [PDF]
Palmier A, Bezzina A.
europepmc +1 more source
RDH11 is a minor isoenzyme that catalyses the oxidation of 11‐cis‐retinol to 11‐cis‐retinal in the retinal pigment epithelium, alongside RDH5 and RDH10. Biallelic null variants in RDH11 lead to upregulation of RDH5 and RDH10 (transcriptional adaptation), maintaining 11‐cis‐retinal bioavailability, but still causing Retinal Pigment Epitheliopathy due to
Kirk A. J. Stephenson +11 more
wiley +1 more source
Eccentricity-Dependent Reflectivity Rates-of-Change Across the Retina in Intermediate Age-Related Macular Degeneration. [PDF]
Trinh M +5 more
europepmc +1 more source
Clinical and multimodal imaging characteristics of acute central serous chorioretinopathy with fibrinous exudation. [PDF]
Liu ZC, Zhang J, Han JD.
europepmc +1 more source
Qiju Granule alleviates retinal damage in a mouse model of age-related macular degeneration. [PDF]
Chen Q, Zhang J, Xu K, Liu X, Liang L.
europepmc +1 more source
Novel Clinical Observations after Photodynamic Therapy in Choroidal Osteoma: A Three-Case Series. [PDF]
Elizalde J, Abengoechea S, Bruix A.
europepmc +1 more source
Reduced Macular Pigment Optical Volume Is Linked to High-Risk OCT Biomarkers and Lower Contrast Sensitivity Function in iAMD. [PDF]
Nodecker KN +18 more
europepmc +1 more source

