Results 271 to 280 of about 77,765 (343)

Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age‐Related Macular Degeneration

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
A Bruchs membrane (BrM) mimic based on aged decellularized BrM was developed and differentially expressed proteins in aged dECM‐BrM that may provide specific biochemical cues fundamental to model AMD in vitro were identified. RPE culture on aged dECM‐BrM developed certain AMD‐like features including reduced TEER and expression of drusen components ...
Blanca Molins   +8 more
wiley   +1 more source

Morphological and Imaging Characterization of the Eye and Adnexa of the Lesser Anteater (Tamandua tetradactyla)

open access: yesAnatomia, Histologia, Embryologia, Volume 55, Issue 3, May 2026.
ABSTRACT The southern tamandua (Tamandua tetradactyla) is a species vulnerable to environmental disturbances, largely due to increasing overlap between its natural habitat and anthropogenically modified landscapes. Detailed anatomical knowledge of the eye and orbital structures, supported by imaging and histological analyses, is essential to improve ...
Estela Larissa Silva dos Santos   +10 more
wiley   +1 more source

Choroidal vascular hyperpermeability patterns in central serous chorioretinopathy correlate with microperimetry: CERTAIN study report 4

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 288-295, May 2026.
Abstract Purpose This report evaluates the association of three distinct leakage patterns of choroidal vascular hyperpermeability (CVH) on indocyanine green angiography (ICGA), previously correlated with disease chronicity, with retinal sensitivity measured by microperimetry in central serous chorioretinopathy (CSC): unifocal indistinct signs of ...
Jennifer M. Chang‐Wolf   +7 more
wiley   +1 more source

Bi-allelic variants in AP5Z1 and AP5B1 lead to retinal degeneration. [PDF]

open access: yesHGG Adv
Hussain HMJ   +11 more
europepmc   +1 more source

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 296-304, May 2026.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem   +5 more
wiley   +1 more source

Fluid/function correlation using AI‐based quantification versus central subfield thickness in treatment‐naïve and pre‐treated patients with neovascular AMD in a real‐world setting

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 305-313, May 2026.
Abstract Purpose To investigate the association between best‐corrected visual acuity (BCVA) and quantitative macular fluid volumes, compared to central subfield thickness (CST) in treatment‐naïve and previously treated patients with active neovascular age‐related macular degeneration (nAMD).
Anna Eidenberger   +15 more
wiley   +1 more source

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