Results 81 to 90 of about 77,821 (282)

Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery

open access: yesMolecular Therapy: Nucleic Acids, 2017
Pigment epithelium derived factor (PEDF) is a potent antiangiogenic, neurotrophic, and neuroprotective molecule that is the endogenous inhibitor of vascular endothelial growth factor (VEGF) in the retina.
Laura Garcia-Garcia   +15 more
doaj   +1 more source

A comprehensive embryonic staging series of the turtle Trachemys scripta

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian   +6 more
wiley   +1 more source

Disk shedding in the absence of a pigment epithelium in the lizard parietal eye

open access: yesVision Research, 1993
The photoreceptors and pigment epithelia of vertebrate retinas rhythmically synthesize and degrade photosensitive membrane, but the origin of the signal to shed the outer segment tips remains unknown. The parietal eye of lizards contains cone-like photoreceptors but no pigment epithelium.
Ahmed, Jameel, Engbretson, G.
openaire   +3 more sources

Idiopathic pigmented vitreous cyst without autofluorescence: a case report

open access: yesBMC Ophthalmology, 2017
Background Vitreous cysts are rare clinical findings and seldom cause visual disturbance. They are generally classified as congenital or acquired and are considered idiopathic when the etiology can not be determined.
Jing Lu, Yan Luo, Lin Lu
doaj   +1 more source

Near-infrared transillumination imaging combined with aperture photometry for the quantification of melanin in the iris pigment epithelium.

open access: yesPLoS ONE, 2020
Near-infrared transillumination is used in the diagnosis and the management of different eye diseases. In particular, it enables the visualization of melanin in the pigment epithelium of the iris.
Maciej Czepita
doaj   +1 more source

A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye [PDF]

open access: yes, 2002
Regulated cell death and survival play important roles in neural development. Extracellular signals are presumed to regulate seven apparent caspases to determine the final structure of the nervous system.
Baker, Nicholas E.   +6 more
core  

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

open access: yes, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson   +8 more
core   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Generation of three induced pluripotent stem cell lines from type 2 diabetic patients with ocular complications

open access: yesStem Cell Research, 2020
Retinopathy is a well-known ocular complication that occurs in patients with type 2 diabetes (T2D). Recent evidence also indicates that diabetic patients have an increased prevalence of dry eye syndrome.
Edward Po-Fan Chu   +8 more
doaj   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

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