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Genetic disorders of pigmentation

Clinics in Dermatology, 2005
More than 127 loci are actually known to affect pigmentation in mouse when they are mutated. From embryogenesis to transfer of melanin to the keratinocytes or melanocytes survival, any defect is able to alter the pigmentation process. Many gene mutations are now described, but the function of their product protein and their implication in melanogenesis
Thierry, Passeron   +2 more
openaire   +2 more sources

Pigmentation Disorders in the Elderly

Drugs & Aging, 2019
Aging skin is subject to morphological change due to both intrinsic (skin tone, genetics, endogenous hormones) and extrinsic (chronic sun exposure, medications, exogenous pigments) factors. The broad spectrum of transformation includes both hypo- and hyperpigmentation.
Andrew M, Armenta   +2 more
openaire   +2 more sources

Disorders of Pigmentation

Primary Care: Clinics in Office Practice
Disorders of pigmentation encompass a wide range of conditions categorized into hyperpigmentation, hypopigmentation, and depigmentation, each with distinct etiologies, clinical presentations, and implications. This article outlines the pathophysiology, clinical features, diagnostic approaches, and management strategies for these pigmentary disorders ...
Ankitaben, Han   +2 more
openaire   +2 more sources

Genetic Disorders of Pigmentation

1994
Disorders of pigmentation were among the first genetic disorders recognized in humans. The distinctive phenotypes of oculocutaneous albinism (OCA) and piebaldism were known to the ancient Greeks and Romans, and the typical clinical features, modes of inheritance, and genetic heterogeneity of these disorders are apparent even in classical descriptions ...
R A, Spritz, V J, Hearing
openaire   +2 more sources

Disorders of Pigmentation

1983
Skin color can be categorized according to whether it is hypopigmented (lighter than normal skin) or hyperpigmented (darker than normal skin). Pigmentation can be melanin- related or not melanin-related. We consider here only color changes; pigmented tumors, both benign and malignant, are considered in Chapters 20 and 21.
Theodor Nasemann   +2 more
openaire   +1 more source

Disorders of Pigmentation

2017
Human variability is most strikingly defined by variations in skin and hair color. Skin pigmentation is primarily a result of melanocyte functioning. However, surrounding keratinocytes, extracellular matrix proteins and dermal fibroblasts also play a role in cutaneous homeostasis and the phenotypic demonstration of color.
Thuy L. Phung   +3 more
openaire   +2 more sources

Pigment Disorders and Pigment Manipulations

2012
Diseases of the pigment system are common worldwide. They may cause a decrease in quality of life, especially in people of color. Moreover, in some people of color, a normal skin itself can cause problems because these individuals do not accept their natural dark color and strive for a lighter complexion to hopefully increase their quality of life ...
openaire   +1 more source

Disorders Of Pigmentation

1985
Inflammatory changes in the skin are a common feature of many skin disorders; similar changes also occur after trauma to the skin particularly after burns. In some instances there is increased pigmentation (Figure 33), whilst in others there is decreased pigmentation (Figure 34).
L. Fry, M. N. P. Cornell
openaire   +1 more source

Pigment Disorders

Australasian Journal of Dermatology, 2022
Cox, Charlotte, Khosrotehrani, Kiarash
openaire   +3 more sources

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