Results 61 to 70 of about 621,146 (257)

Protocol for the MoleMate™ UK Trial: a randomised controlled trial of the MoleMate system in the management of pigmented skin lesions in primary care [ISRCTN 79932379]

open access: yesBMC Family Practice, 2010
Background Suspicious pigmented lesions are a common presenting problem in general practice consultations; while the majority are benign a small minority are melanomas. Differentiating melanomas from other pigmented lesions in primary care is challenging:
Wilson Edward CF   +10 more
doaj   +1 more source

Oral pigmented lesions: a pragmatic approach to diagnosis and management

open access: yes
Diagnosis and management of oral pigmented lesions can be challenging in clinical practice owing to their variable aetiology and different prognoses that range from benign, physiological conditions to systemic disorders, localised mucosal abnormalities ...
Thomson, Peter
core   +1 more source

Dermatoscopy of flat pigmented facial lesions

open access: yes, 2014
BackgroundThe diagnosis of flat pigmented lesions on the face is challenging because of the morphologic overlap of biologically different lesions and the unknown significance of dermatoscopic ...
Rosendahl, C., Kittler, H., Tschandl, P.
core   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Ipsilateral presentation of ocular surface squamous neoplasia and conjunctival melanoma in xeroderma pigmentosum: A rare occurrence

open access: yesIndian Journal of Ophthalmology, 2019
A case of a 16-year-old male with xeroderma pigmentosum (XP) who presented with multiple pigmented and nonpigmented conjunctival lesions in both eyes is reported.
Deepanjali Arya, Sima Das, Arpan Gandhi
doaj   +1 more source

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina. [PDF]

open access: yes, 2014
Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their ...
Ortín-Martínez, A   +8 more
core  

Automated diagnosis of pigmented skin lesions

open access: yes, 2002
Since advanced melanoma remains practically incurable, early detection is an important step toward a reduction in mortality. High expectations are entertained for a technique known as dermoscopy or epiluminescence light microscopy; however, evaluation of
PEROTTI, R.   +10 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

Dermoscopy of facial flat pigmented lesions: a series of 406 cases

open access: yesRevista da Sociedade Portuguesa de Dermatologia e Venereologia
Objective: The diagnosis of facial pigmented lesions remains challenging due to overlapping clinical and dermoscopic features, particularly in individuals with darker phototypes. This study aimed to evaluate and compare the dermoscopic characteristics of
Salma Kozmane, Fatima Zahra-Mernissi
doaj   +1 more source

Electronics‐Free Visual Monitoring of Dry Eye Disease‐Related Tear Biomarkers Using Smart Scleral Lenses

open access: yesAdvanced Science, EarlyView.
An electronics‐free smart scleral lens passively monitors dry eye disease‐related tear biomarkers through colorimetric sensing of chloride, pH, and ocular surface temperature. Smartphone‐assisted image analysis enables quantitative interpretation, providing a simple, non‐invasive strategy for ocular health monitoring without integrated electronics ...
Ziheng Wang   +15 more
wiley   +1 more source

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