Results 141 to 150 of about 635,253 (366)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

open access: yesAdvanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong   +12 more
wiley   +1 more source

Topologically Structured PLLA Fibers With Stress Concentration Effects for Health Monitoring

open access: yesAdvanced Science, EarlyView.
In this study, a multi‐path strategy was developed to enhance the piezoelectric properties of PLLA fibers through the stress concentration effect. The optimized devices generate piezoelectric output up to 14 times that of pure PLLA fibers. This piezoelectric enhancement strategy offers a new approach for high‐performance piezoelectric devices, with ...
Longfei Li   +8 more
wiley   +1 more source

Breeding against osteochondrosis : phenotypic and genetic analyses in horses and pigs

open access: yes, 2011
Osteochondrosis (OC) is a disturbance in the process of endochondral ossification during skeletal growth. The objectives of this thesis were to assess the prevalence and genetic parameters of OC, and to facilitate optimization of breeding against OC ...
Grevenhof, E.M., van   +1 more
core  

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

open access: yesAdvanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan   +7 more
wiley   +1 more source

Addition of oat hulls to an extruded rice-based diet for weaner pigs ameliorates the incidence of diarrhoea and reduces indices of protein fermentation in the gastrointestinal tract

open access: yes, 2008
An experiment was conducted to determine whether adding oat hulls to weaner pig diets based on extruded rice or unprocessed wheat influenced post-weaning diarrhoea (PWD) and protein fermentation in the large intestine.
Pluske, J.R.   +3 more
core  

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun   +11 more
wiley   +1 more source

A high dietary concentration of inulin is necessary to reduce the incidence of swine dysentery in pigs experimentally challenged with Brachyspira hyodysenteriae

open access: yes, 2011
A total of sixty surgically castrated male pigs (Large White × Landrace) weighing 31•2 (sd 4•3) kg were used in a randomised block experiment to examine the effect of added dietary inulin (0, 20, 40 and 80 g/kg) on the occurrence of swine dysentery (SD ...
Phillips, N.D.   +7 more
core  

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