Results 91 to 100 of about 4,364,730 (221)

Crystal structure of human NIF3‐like protein reveals dynamic hexameric assembly with a single divalent metal binding site

open access: yesThe FEBS Journal, EarlyView.
We present the first crystal structures of human NIF3, revealing a dynamic, hexameric ring with a central cavity regulated by flexible insertion domains. Crucially, human NIF3 features a mononuclear zinc‐binding site, marking a distinct evolutionary departure from the dinuclear centers of bacterial homologs.
Elżbieta Wątor‐Wilk   +6 more
wiley   +1 more source

Rice Exo70 interacts with a fungal effector, AVR-Pii, and is required for AVR-Pii-triggered immunity

open access: yes, 2015
Vesicle trafficking including the exocytosis pathway is intimately associated with host immunity against pathogens. However, we still have insufficient knowledge about how it contributes to immunity, and how pathogen factors affect it.
Koki Fujisaki   +21 more
core   +1 more source

The Cytosolic Iron–Sulfur Cluster Assembly Targeting Complex Is Hijacked by Magnaporthe Effector AvrPi9 to Suppress Rice Resistance

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The cytosolic iron–sulfur (Fe‐S) cluster assembly (CIA) targeting complex mediates the maturation of cytosolic and nuclear Fe‐S proteins and governs core eukaryotic cellular processes. However, whether this complex contributes to plant disease resistance remains unclear.
Huanbin Shi   +10 more
wiley   +1 more source

Structural basis and target-specific modulation of ADP sensing by the Synechococcus elongatus PII signaling protein

open access: yes, 2014
PII signaling proteins comprise one of the most versatile signaling devices in nature and have a highly conserved structure. In cyanobacteria, PipX and N-acetyl-L-glutamate kinase are receptors of PII signaling, and these interactions are modulated by ...
Fokina, O.   +5 more
core   +1 more source

Charakterisierung der PII-P Phosphatase in Cyanobakterien [PDF]

open access: yes, 2001
In Cyanobakterien wird das Signaltransduktionsprotein PII in Abhängigkeit der Kohlenstoff- und Stickstoffversorgung der Zellen durch eineKinase phosphoryliert und durch eine Mg2+-abhängige Phosphatase dephosphoryliert.
Irmler, Angelika
core   +1 more source

Nitrogen Metabolism in Sinorhizobium meliloti–Alfalfa Symbiosis: Dissecting the Role of GlnD and PII Proteins

open access: yesMolecular Plant-Microbe Interactions, 2012
To contribute nitrogen for plant growth and establish an effective symbiosis with alfalfa, Sinorhizobium meliloti Rm1021 needs normal operation of the GlnD protein, a bifunctional uridylyltransferase/uridylyl-cleavage enzyme that measures cellular ...
Svetlana N. Yurgel   +2 more
doaj   +1 more source

α-Ketoglutarate Controls the Ability of the Escherichia coli PII Signal Transduction Protein To Regulate the Activities of NRII (NtrB) but Does Not Control the Binding of PII to NRII [PDF]

open access: yesBiochemistry, 2009
PII signal transduction proteins are among the most widely distributed signaling proteins in nature; these proteins are direct sensors of alpha-ketoglutarate and adenylylate energy charge and control receptors that are signal transduction proteins, metabolic enzymes, or permeases involved in nitrogen metabolism.
Jiang, Peng, Ninfa, Alexander J.
openaire   +2 more sources

The Rhizobium GstI Protein Reduces the NH4+ Assimilation Capacity of Rhizobium leguminosarum

open access: yesMolecular Plant-Microbe Interactions, 2001
We show that the protein encoded by the glutamine synthetase translational inhibitor (gstI) gene reduces the NH4+ assimilation capacity of Rhizobium leguminosarum.
Rosarita Tatè   +6 more
doaj   +1 more source

Drug Discovery for Snakebite Envenoming: Wanderings Amid Historical Antidotes and Emerging Therapeutic Opportunities

open access: yesChemMedChem, Volume 21, Issue 21, 12 November 2026.
In this review, we provide an overview of selected historical antidotes against snakebite envenomation used in early modern Europe. Then, the evidence‐based antivenom activity of some natural compounds is discussed as resulting from more than two decades of research studies.
Elisa Bianconi   +3 more
wiley   +1 more source

Coexistence of two structurally similar but functionally different PII proteins in Azospirillum brasilense [PDF]

open access: yesJournal of Bacteriology, 1996
The coexistence of two different PII, proteins in Azospirillum brasilense was established by comparing proteins synthesized by the wild-type strain and two null mutants of the characterized glnB gene (encoding PII) adjacent to glnA. Strains were grown under conditions of nitrogen limitation or nitrogen excess.
M, de Zamaroczy   +4 more
openaire   +2 more sources

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