Results 41 to 50 of about 132,129 (241)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Geneza i historia urzędu dziekana

Studia Koszalińsko-Kołobrzeskie, 2020
The Dean’s Office takes its beginning in the Apostolic era, where the Apostles’ assistants were deacons. Through a choreopioscope, Archdeacon and Archpriest, the predecessor of the present Dean, the office changed its character from charitable to charity
Piotr Łowicki
doaj   +1 more source

Experimental and Theoretical Study of One-Way Cyclic Lateral Responses of Piles in Sloping Ground

Applied Sciences, 2022
This study aims to investigate the one-way cyclic lateral responses of piles in sloping ground by means of experimental and theoretical analyses. For this purpose, a series of laboratory model experiments were performed for different cases of cycle ...
Wenzhe Peng, Minghua Zhao, Chaowei Yang, Shuai Zhou   +3 more
doaj   +1 more source

Development of LRFD Procedures for Bridge Pile Foundations in Iowa Final Report, June 2010 [PDF]

, 2010
For well over 100 years, the Working Stress Design (WSD) approach has been the traditional basis for geotechnical design with regard to settlements or failure conditions.

core  

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Integral bridge abutments in response to seasonal temperature changes: State of knowledge and recent advances

Frontiers in Built Environment, 2022
Expansion and contraction of integral abutment bridges due to temperature changes force integral bridge abutments (IBAs) to move toward and away from the backfill, thus increasing horizontal earth pressures behind the abutments and inducing bending ...
Hao Liu, Jie Han, Robert L. Parsons
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Development of LRFD Procedures for Bridge Pile Foundations in Iowa, September 2011 [PDF]

, 2011
In response to the mandate on Load and Resistance Factor Design (LRFD) implementations by the Federal Highway Administration (FHWA) on all new bridge projects initiated after October 1, 2007, the Iowa Highway Research Board (IHRB) sponsored these ...

core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Offshore Wind Farm Economic Evaluation Under Uncertainty and Market Risk Mitigation

Energies
Renewable energy systems (RES) are strongly affected by many sources of uncertainty and variability. Nevertheless, traditional technical and economic evaluation methods often neglect uncertainty by deterministically assuming average nominal values, using
Antonio C. Caputo, Alessandro Federici, Pacifico M. Pelagagge, Paolo Salini   +3 more
doaj   +1 more source