Results 231 to 240 of about 158,501 (299)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

open access: yesAdvanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya   +10 more
wiley   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

open access: yesAdvanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu   +8 more
wiley   +1 more source

Late Miocene Arctic warmth and terrestrial climate recorded by North Greenland speleothems. [PDF]

open access: yesNat Geosci
Moseley GE   +13 more
europepmc   +1 more source

Genetic Diversity of Legionella pneumophila Isolates from Artificial Water Sources in Brazil. [PDF]

open access: yesCurr Microbiol
Ferrari DDM   +7 more
europepmc   +1 more source

Discovery of microbial glycoside hydrolases <i>via</i> enrichment and metaproteomics. [PDF]

open access: yesRSC Chem Biol
van Ede JM   +4 more
europepmc   +1 more source

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