Results 41 to 50 of about 49,936 (303)
The spectrum of the recycled PSR J0437-4715 and its white dwarf companion
, 2011 We present extensive spectral and photometric observations of the recycled pulsar/white-dwarf binary containing PSR J0437-4715, which we analyzed together with archival X-ray and gamma-ray data, to obtain the complete mid-infrared to gamma-ray spectrum ...
Abdo +43 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Strength of reinforced concrete pile caps [PDF]
Structures <html_ent glyph="@amp;" ascii="&"/> Buildings, 2003 Discrepancies exist in the provisions for the design of reinforced concrete pile caps with regard to shear, between the two UK codes for structural concrete design, namely BS 8110 and BS 5400. These discrepancies have arisen in the historical development of the codes, and the implication is that one code is unsafe or the other is over-conservative ...
Bloodworth, A.G. +2 more
openaire +2 more sources
Evidence for precession of the isolated neutron star RX J0720.4-3125
, 2006 The XMM-Newton spectra of the isolated neutron star RX J0720.4-3125 obtained over 4.5 years can be described by sinusoidal variations in the inferred blackbody temperature, the size of the emitting area and the depth of the absorption line with a period ...
De Vries, C. P. +6 more
core +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
THE RESEARCH OF THE VARIATION LAWS OF SETTLEMENT AND INTERNAL FORCE OF PILE GROUPS OF RAILWAY BRIDGE CAUSED BY PUMPING BRINE [PDF]
Civil Engineering Journal, 2019 Taking Yingzigou Bridge of Dezhou-Dajiawa railway as the engineering background, the three-dimensional fluid-solid coupling models of pile group caps were established on the basis of five-stage field monitoring data of the settlement and groundwater ...
Guodong Li +3 more
doaj +1 more source
Extremely low long‐term erosion rates around the Gamburtsev Mountains in interior East Antarctica [PDF]
, 2010 The high elevation and rugged relief (>3 km) of the Gamburtsev Subglacial Mountains (GSM) have long been considered enigmatic. Orogenesis normally occurs near plate boundaries, not cratonic interiors, and large‐scale tectonic activity last occurred in ...
Cox, S. E. +4 more
core +2 more sources
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Geology of Tindfjallajökull volcano, Iceland [PDF]
, 2018 The geology of Tindfjallajökull volcano, southern Iceland, is presented as a 1:50,000 scale map. Field mapping was carried out with a focus on indicators of past environments.
Dave McGarvie +10 more
core +3 more sources
Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis
Arthritis Care &Research, Accepted Article.Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham +14 more
wiley +1 more source