Results 91 to 100 of about 151,970 (303)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

On Self-Organized Criticality and Synchronization in Lattice Models of Coupled Dynamical Systems

, 1996
Lattice models of coupled dynamical systems lead to a variety of complex behaviors. Between the individual motion of independent units and the collective behavior of members of a population evolving synchronously, there exist more complicated attractors.
Arenas, A., Christensen, K., Corral, A., Díaz-Guilera, A., Pérez, C. J.   +4 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

In-situ investigation on installation mechanisms of pre-bored grouted planted piles in deep and thick sand layers

Soils and Foundations
Due to merits of low noise and vibration, the pre-bored planted method has been widely used in engineering practice to assist the installation of the prestressed high-strength concrete (PHC) piles in area where deep and thick sand layers are commonly ...
Jingwei Zhang, Zhencai Luo, Yunlong Liu, Bowen Zheng, Zhenguo Hou, Jin Kong   +5 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Vibratory Pile Driving in High Viscous Soil Layers: Numerical Analysis of Penetration Resistance and Prebored Hole of CEL Method

Buildings
High-viscosity stratified strata, characterized by complex geotechnical properties such as strong cohesion, low permeability, and pronounced layered structures, exhibit significant lateral friction resistance and high-end resistance during steel sheet ...
Caihui Li, Changkai Qiu, Xuejin Liu, Junhao Wang, Xiaofei Jing   +4 more
doaj   +1 more source

Did the pile driving during the construction of the Offshore Wind Farm Egmond aan Zee, the Netherlands, impact porpoises? [PDF]

The Dutch consortium "NoordzeeWind" has built the first offshore wind farm in Dutch North Sea waters, known as "Offshore Wind farm Egmond aan Zee" (OWEZ) Part of the construction works consisted of driving 36 monopiles into the sea floor, during April ...
Camphuysen, C.J., Leopold, M.F.
core   +2 more sources