Results 81 to 90 of about 151,970 (303)

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Influence of Soil Plugging on Dynamic Soil Response During Simulated Pipe Pile Driving Model Test in Sands

open access: yesApplied Sciences
The squeezing effect and strike-induced vibration generated by pile driving pose a threat to adjacent structures. To mitigate the squeezing effect, open-ended pipe piles were implemented. However, this type of pile brings a degree of soil-plugging effect,
Songchao Lin, Ye Lu, Chong Zhao
doaj   +1 more source

Transport in Sand Piles, Interface Depinning, and Earthquake Models

open access: yes, 1996
Recent numerical results for a model describing dispersive transport in rice piles are explained by mapping the model to the depinning transition of an interface that is dragged at one end through a random medium.
Boettcher, Stefan, Paczuski, Maya
core   +2 more sources

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Acoustic monitoring and analyses of air gun, pile driving, vessel, and ambient sounds during the 2015 seismic surveys on the Sakhalin shelf. [PDF]

open access: yesEnviron Monit Assess, 2022
Rutenko AN   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

DRIVEN POLYSTRONG REINFORCED CONCRETE PILES AND NEW DESIGN OF PILE CAPS

open access: yesНаука и техника, 2015
The paper presents constructional and technological features for manufacturing driven piles with variable strength of pile shaft. Economical efficiency of their production has been shown in the paper.
I. I. Bekbasarov, G. I. Isakov
doaj  

Fatigue Damage Characteristics of Offshore Wind Power Large-Diameter Monopile Structures During Driving Process

open access: yes南方能源建设
[Objective] Large-diameter monopile foundations are widely used in marine engineering in China and are typically installed through penetration. Due to the impact of the pile hammer, the pile body experiences continuous impact loads during the driving ...
Tao CHEN   +4 more
doaj   +1 more source

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