Results 71 to 80 of about 151,970 (303)

Internal Force Analysis of Buried-boring Piles in the Yuanzishan Landslide

open access: yesApplied Sciences, 2020
The Yuanzishan landslide is an unstable slope in Langzhong County, located in northeast Sichuan province, China. The Guangyuan-Nanchong expressway passes through the front edge of the unstable slope, and subgrade excavation has resulted in slope ...
Hao Wang   +5 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Dynamic Effect of Pile Installation in Sand on Nearby Piles

open access: yesمجلة النهرين للعلوم الهندسية, 2017
Driven piles have often been used in many civil structures to provide structural loading support. However, the unavoidable vibrations induced by pile driving processes may cause varying degrees of damage to adjacent structures.
Talib K. Qassim AlSheakayree   +2 more
doaj  

Korelasi Penentuan Daya Dukung Tiang Cara Empirik (Cpt) Dengan Pile Driven Analysis (Pda) Di Kota Pekanbaru [PDF]

open access: yes, 2007
Axial bearing capacity of pile foundation can be estimated empirically from cone penetration test (CPT). Actual capacity of foundation can be obtained from static load test or pile driving analyzer (PDA).
Nugroho, S. (SA), Yusa, M. (Muhamad)
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Jumping the Gap: The Formation Conditions and Mass Function of Pebble-Pile Planetesimals [PDF]

open access: yes, 2015
In a turbulent proto-planetary disk, dust grains undergo large density fluctuations and under the right circumstances, these grain overdensities can overcome shear, turbulent, and gas pressure support to collapse under self-gravity (forming a "pebble ...
Hopkins, Philip F.
core   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Measurements of underwater piling noise during nearshore windfarm construction in the UK potential impact on marine mammals in compliance with German UBA limit [PDF]

open access: yes
Offshore construction work, such as pile and conductor driving, can potentially cause acoustic disturbance to marine mammals, such as cetaceans (whales, dolphins and por-poises), the odontocetes (toothed cetaceans) of which rely on the underwater sound ...
Ford, Benjamin   +3 more
core  

Anomalous Transport in Conical Granular Piles

open access: yes, 2002
Experiments on 2+1-dimensional piles of elongated particles are performed. Comparison with previous experiments in 1+1 dimensions shows that the addition of one extra dimension to the dynamics changes completely the avalanche properties, appearing a ...
A. Corral   +26 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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