Results 71 to 80 of about 9,169,343 (304)

Influence of Pile Spacing on the Compressive Bearing Performance of CEP Groups

Buildings
Pile spacing is an important factor affecting the bearing capacity of concrete expansion pile (CEP) groups. In this study, a pile group was simulated and analyzed using ANSYS software R19.0.
Yongmei Qian, Qingzhi Cao, Yang Yang, Da Teng, Tingting Zhou   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The thermal behaviour of three different auger pressure grouted piles used as heat exchangers [PDF]

, 2014
Three auger pressure grouted (APG) test piles were constructed at a site in Richmond, Texas. The piles were each equipped with two U-loops of heat transfer pipes so that they could function as pile heat exchangers.
Brettmann, T, Brettmann, Tracy, Powrie, W., Olgun, CG, Powrie, W, Powrie, William, Loveridge, F, Olgun, C.G., Brettmann, T., Loveridge, F., Loveridge, Fleur, Olgun, C. Guney   +11 more
core   +1 more source

Study on calculating method of pile group under lateral loading

, 1997
A series of model tests of pile group( two piles in line) were conducted in dry sand under lateral loading with different pile spacing. All of piles were instrumented with strain gauges at different depth in order to obtain soil resistance of each pile ...
王梅, 楼志刚, Wang, M (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China.   +2 more
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Dynamic response analysis of a large-diameter steel tube pile group subjected to hammering loads

Yantu gongcheng xuebao, 2017
A large-diameter steel tube pile is used in a machinery factory in Shanghai to test the new produced diesel pile hammer. However, with the increase of the diesel hammer weight, it fails to meet the test requirements and a pile group is recommended to ...
FENG Shi-jin 1, 2, WANG Lei 1
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Antea Group Archeologie 2020/135

, 2022
In juli 2020 heeft Antea Group in opdracht van Panattoni een archeologisch onderzoek uitgevoerd voor het plangebied ‘DD Panattoni’ te Moerdijk, gemeente Moerdijk. De aanleiding voor het bureauonderzoek is de door Panattoni voorgenomen ontwikkeling van de
Uffink, V. (Antea Group), Brokke, A.J.
core   +1 more source