Results 71 to 80 of about 20,995 (312)
Analysis of Pile Group under Vertical Loading in Clay and Sand using FEM
B A Brunda, G Srilakshmi, H A Ajay
openalex +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Based on the stress field calculated by the Mindlin stress theory with the pile diameter effect considered and the existing Mindlin homogenization stress summation method for calculating the settlement of pile group foundation, the deformation behavior ...
WANG Tao 1,2, LIU Jin-li 1,2, WANG Xu 1,2
doaj +1 more source
Numerical analysis of pile group, piled raft, and footing using finite element software PLAXIS 2D and GEO5. [PDF]
Chimdesa FF +8 more
europepmc +1 more source
Comparison of the Behavior for Free Standing Pile Group and Piles of Piled Raft
The intended task of this paper is studying the behavior of free standing pile groups and piles of piled raft driven in clayey soil under axial loading. The raft-piles interaction is investigated as well through the two series of tests. Each one of these series includes twelve tests, the two series are conducted with the same configuration, spacing ...
Awf Al-Kaisi +2 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A Study of Horizontal Displacement of Laterally Loaded Piles
A theoretical approach is used to analyze single pile and pile in group under lateral loading using two programs. The first one used the finite element method for single pile depending on plain strain condition while the second one used the ...
Aram M. Raheem
doaj

