Results 81 to 90 of about 9,169,343 (304)

Experimental study on vertical bearing behavior of single pile and pile groups in saline soil ground

Yantu gongcheng xuebao
To study the vertical bearing behavior of single pile and pile groups in layered saline soil foundations, laboratory reduced-scale model tests including models of a single pile, two piles, four piles and six piles in saline soil foundations with ...
CAO Xiaolin 1, XUE Lianbin 1, ZHOU Fengxi 1, DAI Guoliang 2
doaj   +1 more source

Homogenized additional stress coefficient of foundation piles based on generalized mode of pile shaft resistance

Yantu gongcheng xuebao, 2018
Based on the stress field calculated by the Mindlin stress theory with the pile diameter effect considered and the existing Mindlin homogenization stress summation method for calculating the settlement of pile group foundation, the deformation behavior ...
WANG Tao 1,2, LIU Jin-li 1,2, WANG Xu 1,2
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Antea Group Archeologie 2020/204

, 2021
N.B.: Het onderzoek is voorgelegd aan en beoordeeld door de bevoegde overheid. Deze heeft het onderstaande advies overgenomen. Antea Group heeft in oktober 2020 een inventariserend veldonderzoek door middel van boringen (verkennende fase) uitgevoerd in ...
Fens, R. (Antea Group), Fleuren, I. (Antea Group)   +1 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Model test study on pile group under lateral loading

, 1999
Based on the results of series of laboratory test carried out on aluminum pipe pile groups in sand under lateral loading, the behavior of pile group is analyzed.
王梅, Wu JP, 楼志刚
core   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Comparison of two different models for pile thermal response test interpretation [PDF]

, 2014
Thermal response tests (TRTs) are regularly used to characterise the thermal resistance of borehole heat exchangers and to assess the thermal conductivity of the surrounding ground.
Loveridge, F.A., Powrie, W., Powrie, W, William Powrie, Nicholson, D., Fleur Loveridge, Loveridge, F, Nicholson, D, Duncan Nicholson   +8 more
core   +1 more source

Numerical analysis of pile group, piled raft, and footing using finite element software PLAXIS 2D and GEO5. [PDF]

Sci Rep, 2023
Chimdesa FF, Chimdesa FF, Jilo NZ, Hulagabali A, Babalola OE, Tiyasha T, Ramaswamy K, Kumar A, Bhagat SK.   +8 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source