Results 81 to 90 of about 14,588,988 (348)

Development of LRFD Procedures for Bridge Pile Foundations in Iowa: Volume II: Field Testing of Steel Piles in Clay, Sand, and Mixed Soils and Data Analysis, September 2011

, 2011
In response to the mandate on Load and Resistance Factor Design (LRFD) implementations by the Federal Highway Administration (FHWA) on all new bridge projects initiated after October 1, 2007, the Iowa Highway Research Board (IHRB) sponsored these ...

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Lateral Pile Group Effects [PDF]

, 2020
En jacket er en vanlig benyttet fundamenttype for offshore vindmøller og plattformer. Jacketen består av et fagverk med flere bein som overfører laster til havbunnen.
Rochmann, Fredrik Nilsen
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Numerical Assessment of Laterally Loaded Pile Group Efficiency

, 2021
The key factors governing the lateral response of a pile group include the pile-head connection rigidity, the pile-soil relative stiffness, the pile spacing ratio, the pile group size and the pile/soil nonlinear response.
Stacul S., Vaccaro M., Squeglia N.
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Homogenized additional stress coefficient of foundation piles based on generalized mode of pile shaft resistance

Yantu gongcheng xuebao, 2018
Based on the stress field calculated by the Mindlin stress theory with the pile diameter effect considered and the existing Mindlin homogenization stress summation method for calculating the settlement of pile group foundation, the deformation behavior ...
WANG Tao 1,2, LIU Jin-li 1,2, WANG Xu 1,2
doaj   +1 more source

Some observations on statnamic pile testing [PDF]

, 2006
Limited guidance on usage and methodology is currently available to engineers for the most common rapid load pile test, known as Statnamic. In order to improve the analysis of Statnamic testing in clay soils a full-scale instrumented auger bored pile was
Brown, M. J.; id_orcid, Hyde, A. F. L.
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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Group thermal response testing for energy piles

, 2015
Thermal response testing is an in situ technique for characterising the thermal conductivity of the ground around a borehole heat exchanger. The test has seen renewed interest in recent years as an increasing number of ground heat exchangers are being ...
Loveridge, F.A., Brettmann, T, Brettmann, Tracy, Powrie, W., Loveridge, FA, Olgun, CG, Powrie, W, Powrie, William, Loveridge, F. A., Olgun, C.G., Brettmann, T., Olgun, C. Guney   +11 more
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Field Test of DX Pile Group

, 2011
DX pile is a newly developed variable cross-section pile. Compared to conventional straight pile, it has distinct advantages on bearing capacity and settlement control. However, the bearing mechanism and characteristics of settlement, especially on group
Li Hong Chen, Song Tao Tang
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source