Results 71 to 80 of about 17,411,117 (298)

Development of LRFD Procedures for Bridge Pile Foundations in Iowa: Volume II: Field Testing of Steel Piles in Clay, Sand, and Mixed Soils and Data Analysis, September 2011 [PDF]

open access: yes, 2011
In response to the mandate on Load and Resistance Factor Design (LRFD) implementations by the Federal Highway Administration (FHWA) on all new bridge projects initiated after October 1, 2007, the Iowa Highway Research Board (IHRB) sponsored these ...

core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Nonlinear Analysis of Pile Group Effect of Large Diameter Drill Hole Cast-in-Place Pile

open access: yes, 2011
This paper adopts large diameter drill hole cast-in-place Pile of one Highway Bridge as the study case, using the pile calculatingly program, GPILE, that is a part of the common program software system of finite element method, SAP84, to analysis the ...
Hua Li Zhang   +4 more
core   +1 more source

Modeling the lateral response of pile groups in cohesionless and cohesive soils

open access: yesInternational Journal of Geo-Engineering, 2018
A three-dimensional finite element approach was used to assess the lateral pile and pile group response subjected to pure lateral load. The study evaluated three pile group configurations (i.e. 2 × 1, 2 × 2 and 3 × 2 pile groups) with four values of pile
Jasim M. Abbas Al-Shamary   +2 more
doaj   +1 more source

New Method for Calculating the Settlement of Single Pile and Pile Group in Soft Soil Area

open access: yesAdvances in Civil Engineering, 2020
This paper fits the τ-z curve of a single pile by mathematical methods. Based on the one-dimensional similarity of the τ-z curves, the τ-z curves of single pile under different loads are derived. It studies the distribution of the axial force of a single
Jingjing Xu, Xu Xu, Wenjuan Yao
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Lateral Pile Group Effects

open access: yes, 2020
En jacket er en vanlig benyttet fundamenttype for offshore vindmøller og plattformer. Jacketen består av et fagverk med flere bein som overfører laster til havbunnen. For å oppnå tilstrekkelig bæreevne og stivhet av fundamentet blir peler ofte benyttet. Pelegruppene består hovedsakelig av 2 til 4 peler med liten innbyrdes avstand.
openaire   +1 more source

Effect of pile group.

open access: yes, 2023
This paper presents a mechanical analysis of the foundation of a temporary offshore platform using a temporary embedded eight-leg support structure. The model is simulated using the finite element simulation software MIDAS-3D, with the modified RANS ...
Yan-zhao Yuan (14769237)   +1 more
core   +1 more source

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