Results 41 to 50 of about 2,698,714 (295)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Development of LRFD Procedures for Bridge Pile Foundations in Iowa, September 2011 [PDF]

open access: yes, 2011
In response to the mandate on Load and Resistance Factor Design (LRFD) implementations by the Federal Highway Administration (FHWA) on all new bridge projects initiated after October 1, 2007, the Iowa Highway Research Board (IHRB) sponsored these ...

core  

Calculation of bearing capacity for combined post-grouting bored piles based on settlement control

open access: yesYantu gongcheng xuebao, 2018
It is of great practical significance to determine the bearing capacity of post-grouting piles on the basis of the principle of settlement control. Based on the field static load tests on six large-diameter cast-in-situ bored piles of Shishou Yangtze ...
DAI Guo-liang 1,2, WAN Zhi-hui 1,2, , GONG Wei-ming 1,2, WANG Lei 3
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Analysis of the Shaft Resistance of Nondisplacement Piles in Sand [PDF]

open access: yes, 2008
The paper examines, using numerical modelling, the problem of the limit shaft resistance of non-displacement piles installed in sands. The modelling makes use of an advanced, two-surface-plasticity constitutive model.
Loukidis, D, Salgado, Rodrigo
core   +1 more source

A Comparative Study on the End-Bearing Capacity of Toe-Wing & Spiral Screw Piles in Cohesionless Soil

open access: yesBuildings
The use of screw piles has grown rapidly, yet their varied configurations and behavior in different soils remain key research areas. This study examines the performance of Toe-wing (Tsubasa) and Spiral screw piles with similar tip areas under similar ...
Ahmad Waheed Sahil   +3 more
doaj   +1 more source

Analysis of Load-Settlement Curve Based on Load Transfer at Pile-Soil Interface

open access: yesApplied Sciences, 2022
A field pile loading test was carried out on the Peshawar–Karachi Motorway (PKM) project in Pakistan to show the settling mechanism of bored pile foundation in pulverized soil and the force characteristics of frictional resistance at the pile-soil ...
Danan Ma   +3 more
doaj   +1 more source

The behaviour of laterally loaded two-pile groups [PDF]

open access: yes, 1992
The response of piles and two-pile groups to lateral loading has been studied by field tests and computationally. Due to the lack of field test data and because of uncertainty concerning the pile/soil system it has been suggested that further ...
Arta, M.R., Arta, Mahmood Reza
core  

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Axial Load Test Procedure of Short Bored Pile Foundation Model in the Field for Tip Support Bearing Study

open access: yesJurnal Teknik Sipil
Axial load testing on short drilled pile foundation models in the field requires several criteria to be met, including: depth of the tip support layer, adjustments to the capacity and arrangement of the test equipment so that it can still refer to the ...
A. Nugraha
semanticscholar   +1 more source

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