Results 101 to 110 of about 39,152 (265)

Neuronal damage and memory deficits after seizures are reversed by ascorbic acid? O dano neuronal e o déficit de memória após convulsões são revertidos pelo ácido ascórbico?

open access: yesArquivos de Neuro-Psiquiatria, 2010
The objective of the present study was to evaluate the neuroprotective effects of ascorbic acid (AA) in rats, against the neuronal damage and memory deficit caused by seizures.
Adriana da Rocha Tomé   +2 more
doaj   +1 more source

Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats. [PDF]

open access: yes, 1998
In order to follow the spatial and temporal evolution of neuronal damage, cellular activation and stress responses subsequent to lithium-pilocarpine seizures of various durations in the adult rat, we analyzed the expression of Fos protein and local ...
Baram, TZ   +3 more
core   +2 more sources

Glucocorticoid‐Induced Tumor Necrosis Factor Receptor Ligand: Correlation and Therapeutic Potential for Cognitive Impairment in Temporal Lobe Epilepsy

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Immune checkpoint regulators can improve neurological functions in Alzheimer's disease. However, it remains blurred whether these regulators may ameliorate temporal lobe epilepsy (TLE) and TLE‐related cognitive impairment. This study analyzed the bulk transcriptomic data of human TLE hippocampi by bioinformatics.
Man Li   +3 more
wiley   +1 more source

Construction of a pilocarpine-induced temporal lobe epilepsy model in mice based on severe seizure behavior

open access: yesZhongguo Linchuang Yixue
Objective To explore the approach to establish a temporal lobe epilepsy model via intraperitoneal pilocarpine injection in C57BL/6J mice, and to summarize behavioral indicators predicting successful modeling during the acute phase of epileptic seizures ...
Fangchao TONG   +5 more
doaj   +1 more source

The Blood-Brain Barrier Breakdown During Acute Phase of the Pilocarpine Model of Epilepsy Is Dynamic and Time-Dependent

open access: yesFrontiers in Neurology, 2019
The maintenance of blood-brain barrier (BBB) integrity is essential for providing a suitable environment for nervous tissue function. BBB disruption is involved in many central nervous system diseases, including epilepsy.
Natália Ferreira Mendes   +9 more
doaj   +1 more source

Therapeutics of pilocarpine [PDF]

open access: yes, 1907
Citation: Martin, Henry Alba. Value of spraying in fruit culture. Senior thesis, Kansas State Agricultural College, 1898.Morse Department of Special CollectionsIntroduction: HABITAT.
Cassell, Albert F.
core  

Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery [PDF]

open access: yes, 2016
Background The relationship between monogenic and polygenic forms of epilepsy is poorly understood, and the extent to which the genetic and acquired epilepsies share common pathways is unclear.
Danis, Bénédicte   +14 more
core   +9 more sources

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

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