Results 81 to 90 of about 17,396 (187)

Dose-Dependent Induction of Differential Seizure Phenotypes by Pilocarpine in Rats: Considerations for Translational Potential

Medicina
Background and Objectives: Pilocarpine is used in experimental studies for testing antiepileptic drugs, but further characterization of this model is essential for its usage in testing novel drugs. The aim of our study was to study the behavioral and EEG
Dolika Vasović, Olivera Stanojlović, Dragan Hrnčić, Nikola Šutulović, Milena Vesković, Aleksandar J. Ristić, Nebojša Radunović, Dušan Mladenović   +7 more
doaj   +1 more source

Development and characterization of niosomes loaded mucoadhesive biodegradable ocular inserts for extended release of pilocarpine HCl

Future Journal of Pharmaceutical Sciences
Background Pilocarpine HCl is a non-selective muscarinic receptor agonist that is prescribed for the treatment of glaucoma. The use of pilocarpine conventional eye drops is associated with several side effects, such as loss of visual acuity, and the need
Tamara Ahmad Alotaibi, Affiong Iyire, Shereen Assaf, Eman Zmaily Dahmash   +3 more
doaj   +1 more source

Efficacy and Safety of Pilocarpine Eye Drops Combinations for Treating Presbyopia in a Thai Population: A Randomized Crossover Trial

Siriraj Medical Journal
Objective: This study aimed to assess and compare the effectiveness and side effects of various concentrations of pilocarpine eye drops (1.5%, 1.25%, and 1%), with and without 0.1% brimonidine, in treating presbyopia, specifically in a Thai population.
Thammanoon Surachatkumtonekul, Pinpilai Jutasompakorn, Anchalika Klinniyom, Wasawat Sermsripong, Kiatthida Hokierti, Prapasson Sangsre, Ketchanya Rungsiri   +6 more
doaj  

Pilocarpine [PDF]

Reactions Weekly, 2020
  +4 more sources

Temporal lobe epilepsy and changes in the M current

Revista Mexicana de Neurociencia
Objective: Acquired alterations of ion channel function occur after status epilepticus (SE). Kv7 channels mediate a sustained outward current (IM) that exerts pivotal control over neuronal excitability.
Hugo Solís, Estela López-Hernández
doaj  

Efficacy and safety of pilocarpine as a secretagogue versus artificial tears in the management of dry eye disease. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Elsayed Saad EM, Elbadry Mohammed Mohammed H, Tharwat E, Ali Ayoub AA, Salama Selim OH, Elsayed Abdelhafeez SM, Mohammed Yusef N, Farouk Soltan TA, Abdelhamid Elfar AA, Abdelhalim Ali Ali M.   +9 more
europepmc   +1 more source

From molecular design to antiepileptic evaluation: sulfonamide-pyrazole derivatives as promising neuroactive agents. [PDF]

RSC Adv
Elgohary MK, Alkabbani MA, Ahmed Ibrahim AM, Elsonbaty A, Abubakr A, Mohamed MH, Almehizia AA, Naglah AM, Fares M, Abdel-Aziz HA.   +9 more
europepmc   +1 more source

Enhancing presbyopia treatment: A comparative study of 1% Pilocarpine monotherapy versus combination with 0.09% Bromfenac. [PDF]

Indian J Ophthalmol
Jain A, Sen S, Imchen MT, Gangwar A, Yadav M, Dubey P.   +5 more
europepmc   +1 more source

Author's response Comments on: Efficacy and safety of pilocarpine hydrochloride ophthalmic solution USP 1.25% w/v (PresVu eye drops) versus placebo ophthalmic solution for the treatment of presbyopia - A multicentric clinical trial. [PDF]

Indian J Ophthalmol
Singh P, Garasiya T, Ajila V, Sengupta S, Datta A, Madhivanan N.   +5 more
europepmc   +1 more source

Effects of an orexin receptor 2-selective agonist on salivary secretion in rats. [PDF]

Sci Rep
Ichishima J, Nakakariya M, Kimura H.
europepmc   +1 more source