Results 61 to 70 of about 17,396 (187)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques ‐ Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee   +3 more
wiley   +1 more source

Associations Between Multimorbidity, Polypharmacy and Oral Conditions in Older Adults: A Systematic Review and Meta‐Analysis

open access: yesGerodontology, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis evaluated the relationship between multimorbidity and polypharmacy on the oral health in older adults (aged 75 years or older). The PECO focus question set for this study was, ‘What is the occurrence, association and impact of multimorbidity and polypharmacy on the oral conditions and its ...
Kittipit Srisanoi   +5 more
wiley   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

open access: yesInternal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani   +3 more
wiley   +1 more source

Taurine/Pilocarpine Interaction in the Malnourished Rat Brain: A Behavioral, Electrophysiological, and Immunohistochemical Analysis

open access: yesFrontiers in Neuroscience, 2019
This study aimed to evaluate the possible protective role of taurine on anxiety-like behavior, brain electrical activity and glial cell immunoreactivity in well-nourished and malnourished rats that were treated with a subconvulsing dose of pilocarpine ...
Elian da Silva Francisco   +4 more
doaj   +1 more source

Tempol Protects Against Radiation Injury in the Submandibular Gland Through the β‐Catenin Signaling Pathway

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Radiation damage severely impacts salivary gland function and cell survival, especially in head and neck radiotherapy. Tempol (TPL), a free radical scavenger, has shown protective effects against radiation damage. This research aimed to investigate the protective effects of TPL on radiation‐induced damage in Hs917.T cells and the ...
Jinfeng Wang   +6 more
wiley   +1 more source

Evaluation of the neuroprotective effect of taurine and green tea extract against oxidative stress induced by pilocarpine during status epilepticus

open access: yesJournal of Basic and Applied Zoology, 2015
Status epilepticus (SE) has functional and structural consequences resulting in brain damage. The present study aims to investigate the role of taurine and green tea extract in the neuroprotection against oxidative stress and changes in ...
Neveen A. Noor   +4 more
doaj   +1 more source

Laser Acupuncture on the Management of Xerostomia in Sjögren's Disease: A Randomized Clinical Trial

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives This study evaluated the efficacy of photobiomodulation (PBM) at acupuncture points for managing xerostomia in patients with Sjögren's Disease. Material and Methods In this randomized, double‐blind clinical trial, 50 patients were assigned to PBM group (n = 22) or sham‐PBM group (n = 28).
Matheus Ferreira Linares   +5 more
wiley   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour   +6 more
wiley   +1 more source

Sleep Deprivation and Neuronal Hyperexcitation Share Transcriptomic Signatures

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
This study demonstrated that sleep deprivation induces transcriptomic changes in mice and rats similar to those observed in various models of neuronal hyperexcitation. These findings suggest a potential link between sleep deprivation and neuropsychiatric disorders.
Markos Michail Chatzigiannis   +2 more
wiley   +1 more source

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