Results 61 to 70 of about 17,433 (189)

Associations Between Multimorbidity, Polypharmacy and Oral Conditions in Older Adults: A Systematic Review and Meta‐Analysis

Gerodontology, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis evaluated the relationship between multimorbidity and polypharmacy on the oral health in older adults (aged 75 years or older). The PECO focus question set for this study was, ‘What is the occurrence, association and impact of multimorbidity and polypharmacy on the oral conditions and its ...
Kittipit Srisanoi, Sabrina Maniewicz, Claudio Rodrigues Leles, Gerry McKenna, Frauke Müller, Murali Srinivasan   +5 more
wiley   +1 more source

Taurine/Pilocarpine Interaction in the Malnourished Rat Brain: A Behavioral, Electrophysiological, and Immunohistochemical Analysis

Frontiers in Neuroscience, 2019
This study aimed to evaluate the possible protective role of taurine on anxiety-like behavior, brain electrical activity and glial cell immunoreactivity in well-nourished and malnourished rats that were treated with a subconvulsing dose of pilocarpine ...
Elian da Silva Francisco, Rosângela Figueiredo Mendes-da-Silva, Cássia Borges Lima de Castro, Geórgia de Sousa Ferreira Soares, Rubem Carlos Araújo Guedes   +4 more
doaj   +1 more source

Tempol Protects Against Radiation Injury in the Submandibular Gland Through the β‐Catenin Signaling Pathway

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Radiation damage severely impacts salivary gland function and cell survival, especially in head and neck radiotherapy. Tempol (TPL), a free radical scavenger, has shown protective effects against radiation damage. This research aimed to investigate the protective effects of TPL on radiation‐induced damage in Hs917.T cells and the ...
Jinfeng Wang, Mingjun Xu, Jinghua Zhong, Kui Zhong, Zheng Chen, Chunyu Liu, Chao Liu   +6 more
wiley   +1 more source

Evaluation of the neuroprotective effect of taurine and green tea extract against oxidative stress induced by pilocarpine during status epilepticus

Journal of Basic and Applied Zoology, 2015
Status epilepticus (SE) has functional and structural consequences resulting in brain damage. The present study aims to investigate the role of taurine and green tea extract in the neuroprotection against oxidative stress and changes in ...
Neveen A. Noor, Haitham S. Mohammed, Yasser A. Khadrawy, Heba S. Aboul Ezz, Nasr M. Radwan   +4 more
doaj   +1 more source

Laser Acupuncture on the Management of Xerostomia in Sjögren's Disease: A Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objectives This study evaluated the efficacy of photobiomodulation (PBM) at acupuncture points for managing xerostomia in patients with Sjögren's Disease. Material and Methods In this randomized, double‐blind clinical trial, 50 patients were assigned to PBM group (n = 22) or sham‐PBM group (n = 28).
Matheus Ferreira Linares, Tainá Duarte dos Santos França, Maria Clara Barros Madureira Ferreira, Michele Gomes do Nascimento, Angela Luzia Branco Pinto Duarte, Luiz Alcino Gueiros   +5 more
wiley   +1 more source

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Construction of a pilocarpine-induced temporal lobe epilepsy model in mice based on severe seizure behavior

Zhongguo Linchuang Yixue
Objective To explore the approach to establish a temporal lobe epilepsy model via intraperitoneal pilocarpine injection in C57BL/6J mice, and to summarize behavioral indicators predicting successful modeling during the acute phase of epileptic seizures ...
Fangchao TONG, Yiying CAI, Yuanfang LI, Qiang WANG, Jing DING, Xin WANG   +5 more
doaj   +1 more source

Effect of pilocarpine on the formalin-induced orofacial pain in rats [PDF]

Veterinary Research Forum, 2012
In this study, the effects of subcutaneous (SC) injection of pilocarpine (a cholinomimetic agent) and atropine (a muscarinic receptors antagonist) were investigated on a tonic model of orofacial pain in rats.
Esmaeal Tamaddonfard, Amir Erfanparast, Emad Khalilzadeh   +2 more
doaj