Results 41 to 50 of about 13,685 (188)

KIAA1549: BRAF gene fusion and FGFR1 hotspot mutations are prognostic factors in pilocytic astrocytomas [PDF]

, 2015
Up to 20% of patients with pilocytic astrocytoma (PA) experience a poor outcome. BRAF alterations and Fibroblast growth factor receptor 1 (FGFR1) point mutations are key molecular alterations in Pas, but their clinical implications are not established ...
Adriana C. Carloni, Alessandra Paulino, Aline Paixão Becker, Carlos Clara, Cristovam Scapulatempo-Neto, Dara L. Aisner, Evelyn Musselwhite, Hélio R. Machado, Jamie Sheren, Luciano Neder, Marileila Varella-Garcia, Ricardo S. Oliveira, Rui M. Reis, Yamane   +13 more
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Intramedullary gangliogliomas: histopathologic and molecular features of 25 cases [PDF]

, 2016
Gangliogliomas are uncommon glioneuronal tumors, which usually arise in the cerebral hemispheres and occasionally in the brain stem. Gangliogliomas occurring in the spinal cord are extremely rare. In this study, we analyzed the clinical, histopathologic,
ANTONELLI, MANILA, Dreschmann, Verena, Dörner, Evelyn, Gessi, Marco, GIANGASPERO, FELICE, Gnekow, Astrid, Pietsch, Torsten, Waha, Andreas   +7 more
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A Pilocytic Astrocytoma Mimicking a Clinoidal Meningioma

Case Reports in Radiology, 2014
Pilocytic astrocytomas and meningiomas are benign, primary brain tumors that may involve the optic tract. Classically, the presence of a dural “tail” sign may differentiate a meningioma from other intracranial lesions.
Christopher S. Hong, Norman L. Lehman, Eric Sauvageau   +2 more
doaj   +1 more source

Motor performance after treatment of pilocytic astrocytoma in the posterior fossa in childhood

Cancer Reports, 2022
Background Pilocytic astrocytoma is the most common brain tumour type in childhood located in the posterior fossa, and treated mainly with surgery. These tumours have low mortality, but knowledge concerning its long‐term outcome is sparse.
Ingela Kristiansen, Gunilla E. Frykberg, Anette Höglund, Annette Sondell, Bo Strömberg, Per Frisk   +5 more
doaj   +1 more source

Magnetic resonance imaging of pilocytic astrocytomas in adults with histopathologic correlation: a report of six consecutive cases

Journal of Integrative Neuroscience, 2021
Pilocytic astrocytoma is a WHO grade I tumor usually diagnosed in pediatric patients, and rarely encountered in the adult population. Therefore, available information about the magnetic resonance imaging characteristics of adult pilocytic astrocytoma ...
Alberto Di Napoli, Paolo Spina, Alessandro Cianfoni, Luca Mazzucchelli, Emanuele Pravatà   +4 more
doaj   +1 more source

Challenges in drug discovery for neurofibromatosis type 1-associated low-grade glioma [PDF]

, 2016
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that results from germline mutations of the NF1 gene, creating a predisposition to low-grade gliomas (pilocytic astrocytoma; PA) in young children. Insufficient data and resources represent
Gutmann, David H, Keller, Charles, Pan, Yuan, Ricker, Cora A   +3 more
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Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age [PDF]

, 2015
Pilocytic astrocytoma (PA) is the most common brain tumor in children but is rare in adults, and hence poorly studied in this age group. We investigated 222 PA and report increased aneuploidy in older patients.
Amon, Baker, Barnholtz-Sloan, Barnholtz-Sloan, Chun, Chun, Chun, Cleveland, Collins, Collins, Collins, Compton, Cotman, Coyle, Cui, Di Agostino, Eischen, Eischen, Fletcher, Gandolfi, Gray, Gronych, Grundy, Guadagno, Guadagno, Gutmann, Gutmann, Hasselblatt, Hawkins, Hoffmann, Hoffmann, Hoffmann, Hoffmann, Huether, Jones, Kleihues, Kruchko, Lee, Levine, Li, Liu, Lozano, Lozano, Manfredi, Montagna, Montagna, Paulus, Pekrun, Pellman, Pfister, Prados, Puduvalli, Reifenberger, Rhee, Van den Berghe, Zlotnik   +55 more
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An elderly patient presenting with a primary spinal multifocal intradural extramedullary pilocytic astrocytoma: a case report and review of the literature

BMC Cancer, 2018
Background Pilocytic astrocytoma is a low-grade central nervous system tumor most commonly seen in children. Dissemination from a primary intracranial tumor along the neuroaxis has been described at both presentation and disease progression. However, the
Devin McBride, Zaid Aljuboori, Eyas M. Hattab, Richard Downs, Shiao Woo, Brian Williams, Joseph Neimat, Eric Burton   +7 more
doaj   +1 more source

Primary pilocytic astrocytoma of the cerebellopontine angle in pediatric patient with neurofibromatosis type 1: a case report

Egyptian Journal of Neurosurgery, 2022
Background Cerebellopontine angle tumor (CPA) in pediatrics is rare as compared to adults. We describe a case of pediatric pilocytic astrocytoma presented as a right CPA mass with a concurrent clinical diagnosis of neurofibromatosis type 1 (NF1).
Zaitun Zakaria, Raja Zubaidah Raja Mohd Rasi, Noor Azman A. Rahman   +2 more
doaj   +1 more source

A case of recurrent epilepsy-associated rosette-forming glioneuronal tumor with anaplastic transformation in the absence of therapy. [PDF]

, 2019
Rosette-forming glioneuronal tumor (RGNT) most commonly occurs adjacent to the fourth ventricle and therefore rarely presents with epilepsy. Recent reports describe RGNT occurrence in other anatomical locations with considerable morphologic and genetic ...
Corless, Christopher L, Ferris, Sean P, Grafe, Marjorie, Gultekin, Sakir H, Halfpenny, Aaron, Lawce, Helen, Lucas, Lora, Moore, Stephen, Nazemi, Kellie, Olson, Susan, Perry, Arie, Selden, Nathan, Solomon, David A, Woltjer, Randy, Wood, Matthew D   +14 more
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