Contrast Leakage Patterns from Dynamic Susceptibility Contrast Perfusion MRI in the Grading of Primary Pediatric Brain Tumors [PDF]
BACKGROUND AND PURPOSE: The pattern of contrast leakage from DSC tissue signal intensity time curves have shown utility in distinguishing adult brain neoplasms, but has limited description in the literature for pediatric brain tumors. The purpose of this
Cardinal, Jeremy S. +4 more
core +1 more source
Whilst a range of nutrition support interventions for those undergoing osteosarcoma treatment has been studied and interest is growing, the evidence is fragmented, methodologically weak and indicates wide variation in clinical practice. We identify priority research needed to establish evidence‐based clinical practice guidance.
Laura Sealy +5 more
wiley +1 more source
Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours
Paediatric brain tumors are becoming well characterized due to large genomic and epigenomic studies. Metabolomics is a powerful analytical approach aiding in the characterization of tumors.
Christopher D. Bennett +12 more
doaj +1 more source
Diffuse spinal leptomeningeal spread of a pilocytic astrocytoma in a 3-year-old child
Pilocytic astrocytomas correspond to lowgrade gliomas and therefore metastasize exceedingly rare. However, pilocytic astrocytomas are able to and leptomeningeal dissemination may be seen. What are the treatment options of these cases?
Ameer Alyeldien +5 more
doaj +1 more source
Clinicopathological characteristics of circumscribed high-grade astrocytomas with an unusual combination of BRAF V600E, ATRX, and CDKN2A/B alternations. [PDF]
学位記番号 ...
Murakami, Chiaki +2 more
core
Propionic Acidemia: Gray Matter Disease Meets Subcortical Leukodystrophy
ABSTRACT Imaging literature on propionic acidemia (PA) is predominantly concerned with deep gray matter changes. In order to investigate the spectrum and patterns of MRI changes, 45 MRI scans of 13 patients (0.31–33.2 years) were systematically analyzed. Deep and cortical gray matter changes were associated with acute metabolic decompensation. Striatum
Hannah Fels‐Palesandro +6 more
wiley +1 more source
Background Primary pilocytic astrocytoma of the CPA (Cerebello-pontine angle), in the pediatric age group is an extremely rare entity, with just three cases reported so far.
Dibya Jyoti Mahakul +1 more
doaj +1 more source
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas [PDF]
The most common pediatric brain tumors are low-grade gliomas (LGGs). We used whole-genome sequencing to identify multiple new genetic alterations involving BRAF, RAF1, FGFR1, MYB, MYBL1 and genes with histone-related functions, including H3F3A and ATRX ...
A Gajjar +74 more
core +1 more source
Optic Nerve Pilocytic Astrocytoma in a Pediatric Patient: A Case Report
Pilocytic astrocytoma is a type of low-grade glioma that can develop in any part of the central nervous system. It primarily affects individuals in the pediatric and young adult age groups.
I Made Stepanus Biondi Pramantara +6 more
doaj +1 more source
Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma [PDF]
Low-grade brain tumors (pilocytic astrocytomas) arising in the neurofibromatosis type 1 (NF1) inherited cancer predisposition syndrome are hypothesized to result from a combination of germline and acquired somatic NF1 tumor suppressor gene mutations ...
Demeter, Ryan +14 more
core +2 more sources

