Results 31 to 40 of about 637,360 (196)

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

FuturICT: FET Flagship Pilot Project

Procedia Computer Science, 2011
The ultimate goal of the FuturICT Flagship is to understand and manage complex, global, socially interactive systems, with a focus on sustainability and resilience. Revealing the hidden laws and processes underlying societies constitutes the most pressing scientific grand challenge of our century.
Bishop Steven, Helbing Dirk, Lukowicz Paul, Conte Rosaria   +3 more
openaire   +3 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Pay for Success: Investing in What Works [PDF]

, 2012
Outlines insights from a convening dedicated to the Pay for Success financing model, which directs taxpayer money to successful interventions that address social issues; lessons learned about needed support for pilot projects; and the field's ...

core  

The Science Case for PILOT I: Summary and Overview [PDF]

, 2009
Original article can be found at: http://www.publish.csiro.au/?nid=139&aid=108 DOI: 10.1071/AS08048 [Open access article]PILOT (the Pathfinder for an International Large Optical Telescope) is a proposed 2.5-m optical/infrared telescope to be located ...
Ashley, M. C. B., Bailey, J., Bedding, T., Bertre, T. Le, Bland-Hawthorn, J., Bond, I., Boulanger, F., Bouwens, R., Bruntt, H., Bunker, A., Burgarella, D., Burton, M. G., Busso, M., Cioni, M. -R., Coward, D., Durand, G., Eiroa, C., Epchtein, N., Gehrels, N., Gillingham, P., Glazebrook, K., Haynes, R., Kiss, L., Lagage, P. O., Lawrence, J. S., Mackay, C., Maillard, J. P., McGrath, A., Minier, V., Mora, A., Navascues, D. Barrado y, Olsen, K., Persi, P., Pimbblet, K., Quimby, R., Saunders, W., Schmidt, B., Stello, D., Storey, J. W. V., Tinney, C., Tremblin, P., Wheeler, J. C., Yoc, P.   +42 more
core   +3 more sources

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Professionalism skills education in medical physics residency: Current state and perceived importance

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The purpose of this study was to collect data on current practices for teaching and assessing professionalism in CAMPEP‐accredited residency programs. Methods A survey of 21 questions was sent to 160 program directors (PDs) of CAMPEP‐accredited residency programs.
Anna Rodrigues, Leah Schubert, Laura Padilla, Kristi Hendrickson, Hania Al‐Hallaq, Irina Vergalasova   +5 more
wiley   +1 more source

Letter to Transfair USA regarding Fair Trade Garments Pilot Project [PDF]

, 2009
Letter explaining the Transfair USA’s Fair Trade Garments Pilot Project, which would allow fair trade certification of projects made by workers who are paid poverty wages and denied freedom of association.
International Labor Rights Forum
core   +1 more source

A learning tool to develop sustainable projects [PDF]

, 2016
This paper presents a tool developed to help engineers to design and develop sustainable projects. The tool has been designed to introduce and evaluate the sustainability of engineering projects in general, but here we show its application to assess the ...
Alier Forment, Marc, Cabré Garcia, José M., García Almiñana, Jordi, López Álvarez, David, Martín Escofet, Carme, Sánchez Carracedo, Fermín, Vidal López, Eva María   +6 more
core   +1 more source

Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Prostate Stereotactic Ablative Body Radiotherapy (SABR) is an ultra‐hypofractionated treatment where small setup errors can lead to higher doses to organs at risk (OARs). Although bowel and bladder preparation protocols reduce inter‐fraction variability, inconsistent patient adherence still results in OAR variability.
Conor Sinclair Smith, Isabelle Gagne, Karl Otto, Carter Kolbeck, Joshua Giambattista, Abraham Alexander, Sonja Murchison, Andrew Pritchard, Erika Chin   +8 more
wiley   +1 more source