Results 51 to 60 of about 73,842 (278)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Use of commercial pilot training at Air Force training system to raise the capabilities of IRIAA [PDF]

open access: yesعلوم و فنون نظامی, 2016
Since the Aviation is based on facility, getting benefit of skilled and efficient personnel which are updated with the latest science is quite important.
Seyed Kamal-aldin Seyed Zadeh
doaj  

Editorial for Vol. 33, No. 4

open access: yesHanggong uju uihakoeji, 2023
This issue of Volume 33, Issue 4 contains 4 papers, 2 review articles, 1 letter, 1 case report focusing on aerospace medicine and human factors.
Juwon Lim
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The applicability of King-Devick test in early detection of cognitive impairments due to induced hypoxia in military pilots [PDF]

open access: yesفصلنامه ابن سینا, 2018
Background: Hypoxia is one of the major threats to human health in high altitude. Considering the importance of hypoxia experience by military pilots and educating them how to deal with this condition, this study was designed to assess the applicability ...
S Ehteshami   +5 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Application of smart wearable systems for health monitoring in military [PDF]

open access: yesفصلنامه ابن سینا, 2018
Background: In recent years with the increasing popularity of non­invasive and low-invasive methods, the smart clothing application - either as professional recognizing tools for medical analysis or in domestic usage- has increased. Such systems could be
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doaj  

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