Results 61 to 70 of about 246,509 (289)

Lessons from the English National Health Service new care models programme

open access: yesInternational Journal of Integrated Care, 2019
Introduction: Between 2015 and 2018, the National Health Service (NHS) in England invested over £300m in a New Care Models (NCM) programme to develop new approaches to delivering care to whole populations.
Charles Tallack, Samantha Hinks
doaj   +1 more source

Fighters pilot helmet design for 5th generation aircraft [PDF]

open access: yes, 2013
Fighter pilots’ helmets have become more complex and heavier resulting in long term implications to pilots musculoskeletal systems as they fly and experience high g-load.
Little, Andrew   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

A Flight Path to Well-Being: The Mediating Role of Continuous Learning between Burnout and Work Performance in Aviation Professionals

open access: yesSocial Sciences
The profession of airline pilots is characterized by high levels of stress and a significant risk of burnout. The health emergency period has exacerbated these challenges to health and well-being, with long COVID adding further strain to aviation ...
Cataldo Giuliano Gemmano   +3 more
doaj   +1 more source

Two pilots may be safer than one: The effect of group discussion on perceived invulnerability [PDF]

open access: yes, 2011
Although most general aviation (GA) pilots have received training in aviation decision making, one of the most common causes of GA accidents remains a pilot’s decision to press-on with a flight, when the safe decision was to turn back or divert ...
Gilbey, Andrew, Lee, Seung Yong
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

National Evaluation of the Capacity Building Programme in English Local Government: Annex 1. Seven Case Studies: The Pilot Programme [PDF]

open access: yes, 2008
This report presents the findings of the evaluation of the Capacity Building pilots. The evaluation of the pilots is part of the on-going evaluation of the Capacity Building Programme and has been undertaken in the early scoping phase of the main ...
Dowson, L   +5 more
core  

Tablet-based Information System for Commercial Air-craft: Onboard Context-Sensitive Information System (OCSIS) [PDF]

open access: yes, 2018
Pilots currently use paper-based documentation and electronic systems to help them perform procedures to ensure safety, efficiency and comfort on commercial aircrafts.
Boy, Guy Andre, Tan, Wei
core   +4 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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