Results 21 to 30 of about 56,683 (321)

Structure of the Neisseria meningitidis Type IV pilus

Nature Communications, 2016
Neisseria meningitidis use Type IV pili (T4P) to adhere to endothelial cells and breach the blood brain barrier, causing cause fatal meningitis. T4P are multifunctional polymers of the major pilin protein, which share a conserved hydrophobic N terminus ...
Subramania Kolappan, Mathieu Coureuil, Edward H Egelman   +2 more
exaly   +2 more sources

Bidirectional pilus processing in the Tad pilus system motor CpaF

Nature Communications
The bacterial tight adherence pilus system (TadPS) assembles surface pili essential for adhesion and colonisation in many human pathogens. Pilus dynamics are powered by the ATPase CpaF (TadA), which drives extension and retraction cycles in Caulobacter ...
Michael Hohl, Emma J. Banks, Max P. Manley, Tung B. K. Le, Harry H. Low   +4 more
doaj   +4 more sources

A comprehensive guide to pilus biogenesis in Gram-negative bacteria

Nature Reviews Microbiology, 2017
Manuela K Hospenthal, Tiago R D Costa, Gabriel Waksman   +2 more
exaly   +2 more sources

Dual Role for Pilus in Adherence to Epithelial Cells and Biofilm Formation in Streptococcus agalactiae

PLoS Pathogens, 2009
Streptococcus agalactiae is a common human commensal and a major life-threatening pathogen in neonates. Adherence to host epithelial cells is the first critical step of the infectious process.
Patrick Trieu-Cuot, Shaynoor Dramsi
exaly   +3 more sources

Structure Determination of Microtubules and Pili: Past, Present, and Future Directions

Frontiers in Molecular Biosciences, 2022
Historically proteins that form highly polymeric and filamentous assemblies have been notoriously difficult to study using high resolution structural techniques.
James A. Garnett, Joseph Atherton
doaj   +1 more source

The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation

Nature Communications, 2023
Enteropathogenic bacteria use extracellular appendages, known as F-pili, to share plasmids carrying antibiotic resistance genes. Here, the authors show that F-pili are highly flexible but robust at the same time, and this is important for plasmid ...
Jonasz B. Patkowski, Tobias Dahlberg, Himani Amin, D. K. Gahlot, Sukhithasri Vijayrajratnam, Joseph P. Vogel, M. Francis, Joseph L. Baker, Magnus Andersson, Tiago R. D. Costa   +9 more
semanticscholar   +1 more source

Streptococcus pneumoniae Type 1 Pilus – A Multifunctional Tool for Optimized Host Interaction

Frontiers in Microbiology, 2021
Streptococcus pneumoniae represents a major Gram-positive human pathogen causing bacterial pneumonia, otitis media, meningitis, and other invasive diseases. Several pneumococcal isolates show increasing resistance rates against antibacterial agents.
Stefan Ness, Markus Hilleringmann
doaj   +1 more source

Contributions of F‐specific subunits to the F plasmid‐encoded type IV secretion system and F pilus

Molecular Microbiology, 2022
F plasmids circulate widely among the Enterobacteriaceae through encoded type IV secretion systems (T4SSFs). Assembly of T4SSFs and associated F pili requires 10 VirB/VirD4‐like Tra subunits and eight or more F‐specific subunits.
Kouhei Kishida, Rachel E. Bosserman, Laith Harb, Pratick Khara, Liqiang Song, Bo Hu, Lanying Zeng, P. Christie   +7 more
semanticscholar   +1 more source

F Pilus as f⁺Antigen [PDF]

Journal of Bacteriology, 1967
Specific aggregate formation of F pili was observed, by electron microscopy, in a mixture of maleEscherichia coli(or of isolated F pili) and anti-f+serum. Cellular appendages other than F pili never showed such aggregation when mixed with anti-f+serum.
Masahide Ishibashi
openalex   +3 more sources

Entropic bonding of the type 1 pilus from experiment and simulation [PDF]

Royal Society Open Science, 2020
The type 1 pilus is a bacterial filament consisting of a long coiled proteic chain of subunits joined together by non-covalent bonding between complementing β-strands.
Fabiano Corsetti, Alvaro Alonso-Caballero, Simon Poly, Raul Perez-Jimenez, Emilio Artacho   +4 more
doaj   +1 more source