Results 51 to 60 of about 5,401 (225)

Pimecrolimus, a topical calcineurin inhibitor used in the treatment of atopic eczema [PDF]

, 2013
INTRODUCTION: Pimecrolimus , a calcineurin inhibitor, is a non-steroidal treatment option in patients aged ≥ 2 years with mild-to-moderate atopic eczema (AE).
Prucha, Hanna, Andreas Wollenberg, Schnopp, Christina, Christina Schnopp, Wollenberg, Andreas, Claudia Traidl-Hoffmann, Ring, Johannes, Lauener, Roger, Johannes Ring, Traidl-Hoffmann, Claudia, Hanna Prucha, Roger Lauener, Cezmi Akdis, Akdis, Cezmi   +13 more
core   +2 more sources

Substantiation of Using Pimecrolimus 1% Cream in Proactive Therapy of Children with Atopic Dermatitis

Вопросы современной педиатрии, 2021
Atopic dermatitis (AtD) is multifactorial inflammatory skin disease with high prevalence in pediatric population. It is crucial to implement long-term maintenance therapy to prevent AtD exacerbations according to current clinical guidelines and expert ...
Nikolay N. Murashkin, Roman A. Ivanov, Eduard T. Ambarchian, Roman V. Epishev, Alexander I. Materikin, Leonid A. Opryatin, Alena A. Savelova   +6 more
doaj   +1 more source

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

JEADV Clinical Practice, EarlyView.
Skin samples of Hailey‐Hailey and Darier diseases were analyzed for inflammatory and barrier markers using indirect immunofluorescence and transcriptomic techniques. A mixed Th2/Th17 inflammatory pattern and altered expression of barrier markers were observed.
Ella Glodjajic, Darko Stojkov, Joanna Boros‐Majewska, Jeremy Di Domizio, Michel Gilliet, Christoph Schlapbach, Timothée Fettrelet, Luca Borradori, Hans‐Uwe Simon, Dagmar Simon, Susanne Radonjic‐Hoesli   +10 more
wiley   +1 more source

Dupilumab‐Associated Erythema Multiforme‐Like Eruption With Lichenoid Histology in a Paediatric Patient: A Case Report

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Dupilumab‐associated erythema multiforme and lichenoid eruptions have been previously reported as rare dermatological adverse events. We present an atypical paediatric case of a dupilumab‐associated erythema multiforme‐like eruption in a 5‐year‐old male eczema patient, who developed erythematous targetoid papules and plaques over the upper and
Paul Sun Woo Kim, Jacqueline Tu, Kelvin Truong, Gloria Fong, William Luu, Narinder Kaur, Miriam Fewtrell, Li‐Chuen Wong   +7 more
wiley   +1 more source

Analysis of pruritus (pimecrolimus vs tacrolimus).

, 2014
Analysis of pruritus (pimecrolimus vs tacrolimus).
Youyu Sheng (545451), Chunyun Huang (545450)   +1 more
core   +1 more source

Topical treatment of atopic dermatitis in children: current challenges and answers

Vestnik Dermatologii i Venerologii, 2017
Atopic dermatitis (AD) is the most prevalent skin disease in the early childhood and is a considerable problem both for patients and members of their families and for the society on the whole.
L. S. Namazova-Baranova, N. N. Murashkin, A. I. Materikin, E. T. Ambarchyan, R. V. Epishev   +4 more
doaj   +1 more source

Dupilumab in Paediatric Netherton Syndrome: Two Case Reports and a Review of the Literature

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Netherton Syndrome (NS) is a rare genodermatosis characterised by a triad of ichthyosiform erythroderma, an atopic diathesis, and trichorrhexis invaginata, for which no effective management is currently approved in Australia. Dupilumab has demonstrated considerable effectiveness in the treatment of atopic conditions in the paediatric ...
Jacqueline Tu, Paul Sun Woo Kim, Kelvin Truong, Gloria Fong, William Luu, Li‐Chuen Wong   +5 more
wiley   +1 more source

Discovery of topical calcineurin inhibitors and pharmacological profile of pimecrolimus.

, 2006
Using a newly developed model of allergic contact dermatitis in pigs, calcineurin inhibitors of the tacrolimus and ascomycin type were shown to have a highly anti-inflammatory action after topical application.
Meingassner, Josef, Baumann, Karl, Wolff, Klaus, Stuetz, Anton, Grassberger, Max   +4 more
core   +1 more source

Balanite plasmocitária de Zoon: relato de dois casos tratados com pimecrolimo Zoon's plasma cell balanitis: a report of two cases treated with pimecrolimus

Anais Brasileiros de Dermatologia, 2011
Inicialmente, denominada "Balanoposthite chronique circonscrite benigne a plasmocytes", a balanite plasmocitária de Zoon é uma dermatose inflamatória crônica da glande e prepúcio afetando homens não circuncisados.
Livia Delgado, Hebert Roberto Clivati Brandt, Damaris G Ortolan, Régia Celli Ribeiro Patriota, Paulo Ricardo Criado, Walter Belda Junior   +5 more
doaj   +1 more source

Percutaneous Absorption of Pimecrolimus Is Not Increased in Patients with Moderate to Severe Atopic Dermatitis when Pimecrolimus Cream 1% Is Applied under Occlusion

, 2010
<i>Aim:</i> To evaluate the systemic exposure of pimecrolimus cream 1% applied under occlusion in atopic dermatitis (AD) patients. <i>Methods:</i> A noncomparative, open-label study conducted in 3 groups of moderate to severe AD ...
Diamant Thaçi, Roland Kaufmann, Suzanne Hauffe, Felix Waldmeier, Thomas Bieber, Julia Hanfland, Stephan Koehne-Voss   +6 more
core   +1 more source