Results 71 to 80 of about 5,401 (225)

Limited Efficacy of Autologous Mesenchymal Stromal Cell Injections in Immunomodulatory‐Dependent Dogs With Aqueous Deficient Dry Eye Disease

Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective Aqueous deficient dry eye disease (ADDE) results from a quantitative reduction in aqueous tears. We sought to determine the clinical effect of autologous mesenchymal stromal cell (MSC) injections into the region of the lacrimal gland and the gland of the third eyelid in immunomodulatory‐dependent ADDE‐affected dogs. Methods Dogs (n = 
Brian C. Leonard, Shin Ae Park, Sun Young Kim, Kei Hayashi, Sara M. Thomasy, Vanessa Rozo, Monica J. Motta, Dori L. Borjesson, Christopher J. Murphy, Kathryn L. Good   +9 more
wiley   +1 more source

Topical pimecrolimus inhibits high-dose UVB irradiation-induced epidermal Langerhans cell migration, via regulation of TNF-a and E-cadherin

Drug Design, Development and Therapy, 2014
ZhiQiang Yin,1,* JiaLi Xu,2,* BingRong Zhou,1 Di Wu,1 Yang Xu,1 JiaAn Zhang,1 Dan Luo1 1Department of Dermatology, 2Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Guangzhou Road, Nanjing, Jiangsu, People’s ...
Yin Z, Xu J, Zhou B, Wu D, Xu Y, Zhang J, Luo D   +6 more
doaj  

Pimecrolimus Enhances TLR2/6-Induced Expression of Antimicrobial Peptides in Keratinocytes [PDF]

, 2008
Calcineurin inhibitors are potent inhibitors of T-cell-receptor mediated activation of the adaptive immune system. The effects of this class of drug on the innate immune response system are not known.
Hultsch, Thomas, Gallo, Richard L., Richard L. Gallo, Büchau, Amanda S., Anton Stuetz, Buechau, Amanda S, Thomas Hultsch, Stuetz, Anton, Jürgen Schauber, Schauber, Jürgen, Gallo, Richard L, Amanda S. Büchau   +11 more
core   +1 more source

Treatment of refractory conjunctivitis associated to dupilumab with topical pimecrolimus applied to the eyelid skin

Dermatologic Therapy, 2019
Patients with atopic dermatitis commonly experience ophthalmic complications, and a higher incidence of conjunctivitis has been observed during treatment with dupilumab.
A. Sernicola, Irene Gattazzo, Federico Di Staso, D. Giordano, A. Capalbo, F. Persechino, G. Scuderi, S. Persechino   +7 more
semanticscholar   +1 more source

Milia en plaque – therapeutic response to calcipotriol

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Veronika Hall, Johannes M. Weiss
wiley   +1 more source

Erosive pustular dermatosis of the lower legs (EPDL): A rarely diagnosed neutrophilic dermatosis of the elderly

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 7, Page e880-e885, July 2026.
Summary Erosive pustular dermatosis of the lower legs (EPDL) is a rarely diagnosed, chronic inflammatory skin disease that occurs predominantly in elderly people. Predisposing factors include skin atrophy, chronic venous insufficiency, and trauma. Although the pathogenesis of EPDL has not yet been conclusively clarified, there are ongoing discussions ...
Joachim Dissemond, Jan Kottner, Jan‐Malte Placke, Cornelia Erfurt‐Berge   +3 more
wiley   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, Volume 9, Issue 6, Page 1142-1166, June 2026.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Long-Term Efficacy and Safety of Pimecrolimus Cream 1% in Adults with Moderate Atopic Dermatitis [PDF]

, 2004
Background: Pimecrolimus cream 1% is a non-steroid, selective inflammatory cytokine inhibitor indicated for atopic dermatitis (AD). Objective: To compare the safety and efficacy of pimecrolimus cream 1%-based treatment versus conventional therapy in ...
Meurer, Michael, Altmeyer, Peter Josef, Weidinger, Gottfried, Bräutigam, Matthias, Fartasch, Manige, Albrecht, Gisela, Schneider, Dirk, Vogt, Thomas, Ruzicka, Thomas, Braeutigam, Matthias, Worm, Margitta   +10 more
core   +1 more source

TWO TOPICAL CALCINEURIN INHIBITORS FOR THE TREATMENT OF ATOPIC DERMATITIS IN PEDIATRIC PATIENTS: A META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS (ARTICLE IN ENGLISH)

Педиатрическая фармакология, 2011
Two new topical immunomodulators, pimecrolimus cream and tacrolimus ointment for atopic dermatitis (AD) in pediatric patients, have provided alternatives to topical corticosteroids without the associated adverse events.
S.L. Chen, J. Yan, F.S. Wang
doaj   +2 more sources

Efficacy of combination therapy of pimecrolimus 1% cream and mometasone cream with either agent alone in the treatment of childhood vitiligo

Journal of Pakistan Association of Dermatologists, 2019
  Objective To evaluate the efficacy of the combination therapy of mometasone and pimecrolimus in the treatment of vitiligo in children.   Methods In this double-blind randomized controlled trial, 50 patients were enrolled.
S. Farajzadeh, I. Esfandiarpour, Elham Poor Khandani, Alireza Ekhlasi, Soheyla Safari, Sadegh Hasheminasab Gorji, Mahin Aflatoonian, Saman Mohammadi, Maryam Khalili, B. Vares   +9 more
semanticscholar   +1 more source