Results 51 to 60 of about 518,604 (301)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A comparative evaluation of physical properties of CAD/CAM complete denture resins- an in vitro study

open access: yesBMC Oral Health
Background In dentistry, there is a growing preference for computer-aided design and computer-aided manufacturing (CAD/CAM) systems over traditional laboratory procedures. However, there is not much literature comparing various CAD/CAM materials.
Ojasvini Arora   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Evaluation of the influence of texture and microstructure of titanium substrates on TiO2 anodic coatings at 60 V [PDF]

open access: yes, 2017
The current paper analyzes the influence of texture and microstructure of Ti substrates on morphology and color of titanium dioxide coatings obtained by anodic oxidation.
Ares, Alicia Esther   +5 more
core   +1 more source

Treatment of pediatric supracondylar humerus fractures accompanied with pink pulseless hands

open access: yesBMC Musculoskeletal Disorders, 2021
Background The optimal treatment for pediatric supracondylar humeral fractures accompanied with a pink pulseless hand is controversial. Some clinicians recommend close observation after closed reduction and percutaneous pinning of the fractures, while ...
Li-wei Xie, Juan Wang, Zhi-qiang Deng
doaj   +1 more source

Using a B-Phycoerythrin Extract as a Natural Colorant: Application in Milk-Based Products

open access: yesMolecules, 2021
Nowadays, there is a growing interest in finding new coloring molecules of natural origin that can increase and diversify the offer of natural food dyes already present in the market.
Ana Belén García   +3 more
doaj   +1 more source

Light Reflectance Characteristics and Remote Sensing of Waterlettuce [PDF]

open access: yes, 2003
Waterlettuce ( Pistia stratiotes L.) is a free-floating exotic aquatic weed that often invades and clogs waterways in the southeastern United States.
Everitt, J. H.   +2 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

A pink colored dioxobilin-type phyllobilin from breakdown of chlorophyll [PDF]

open access: yesMonatshefte für Chemie - Chemical Monthly, 2019
In senescent leaves of higher plants, colorless chlorophyll (Chl) catabolites typically accumulate that belong to one of two major types, classified as formyloxobilin-type or dioxobilin-type phyllobilins (PBs). Natural yellow and pink colored formyloxobilin-type PBs are also known, named YCCs and PiCCs, respectively.
Chengjie Li, Bernhard Kräutler
openaire   +1 more source

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