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Reactions Weekly, 2016
Pioglitazone is a thiazolidinedione antidiabetic with actions similar to those of rosiglitazone. It is used in the management of type 2 diabetes mellitus and is prepared by reducing 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzilidene]-2,4-thiazolidinedione with sodium borohydride in the presence of a cobalt ion and dimethyl glyoxime. Ultraviolet spectroscopy
A, Al-Majed +4 more
+5 more sources
Pioglitazone is a thiazolidinedione antidiabetic with actions similar to those of rosiglitazone. It is used in the management of type 2 diabetes mellitus and is prepared by reducing 5-[4-[2-(5-ethyl-2-pyridyl)ethoxy]benzilidene]-2,4-thiazolidinedione with sodium borohydride in the presence of a cobalt ion and dimethyl glyoxime. Ultraviolet spectroscopy
A, Al-Majed +4 more
+5 more sources
Die Pharmazie, 2007
Methods of preparation of API pioglitazone were discussed from the point of view of impurities occurrence. Four real impurities (I–IV) of pioglitazone were prepared and characterized by means of NMR spectroscopy.
J, Richter +3 more
openaire +2 more sources
Methods of preparation of API pioglitazone were discussed from the point of view of impurities occurrence. Four real impurities (I–IV) of pioglitazone were prepared and characterized by means of NMR spectroscopy.
J, Richter +3 more
openaire +2 more sources
Drugs, 2006
A fixed-dose pioglitazone/metformin tablet is approved in the US and the EU for the treatment of adult patients with type 2 diabetes mellitus who currently have inadequate glycaemic control with metformin monotherapy. In the US, the combination tablet is also approved for the treatment of adult patients with type 2 diabetes who currently have ...
Emma D, Deeks, Lesley J, Scott
openaire +2 more sources
A fixed-dose pioglitazone/metformin tablet is approved in the US and the EU for the treatment of adult patients with type 2 diabetes mellitus who currently have inadequate glycaemic control with metformin monotherapy. In the US, the combination tablet is also approved for the treatment of adult patients with type 2 diabetes who currently have ...
Emma D, Deeks, Lesley J, Scott
openaire +2 more sources
Pioglitazone and nephrolithiasis
Kidney International, 2019Sheng-Wen, Niu +2 more
openaire +2 more sources
Pioglitazone and statins lower incidence of Parkinson disease in patients with diabetes mellitus
European Journal of Neurology, 2021Kun-Der Lin, Yu-Hung Chang
exaly