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Phosphatidylinositol 4,5-bisphosphate activation mechanism of human KCNQ5. [PDF]
Yang Z +11 more
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Cell membrane cholesterol affects serotonin transporter efflux due to altered transporter oligomerization. [PDF]
Rudin D +8 more
europepmc +1 more source
Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression. [PDF]
Li X, He X, Sun Y, Yang W.
europepmc +1 more source
An update on regulation of the polymodal TRPV4 channel by protein phosphorylation. [PDF]
Parthasarathy A, Zhang DX.
europepmc +1 more source
PIP<sub>2</sub> promotes the incorporation of CD43, PSGL-1, and CD44 into nascent HIV-1 particles. [PDF]
de Souza Cardoso R +4 more
europepmc +1 more source
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Cholesterol and PIP2 Modulation of BKCa Channels
2023Ca2+/voltage-gated, large conductance K+ channels (BKCa) are formed by homotetrameric association of α (slo1) subunits. Their activity, however, is suited to tissue-specific physiology largely due to their association with regulatory subunits (β and γ types), chaperone proteins, localized signaling, and the channel's lipid microenvironment.
Thirumalini, Vaithianathan +3 more
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Vesicle transport: Exocyst follows PIP2 to tether membranes
Current Biology, 2022A new study uses reconstituted, functional octameric exocyst complex to provide new insights into the assembly of this tethering complex and reveal how the activity of the lipid kinase PIP5K1C stimulated by Arf6 on exocytic vesicles allows for exocyst-mediated tethering at the plasma membrane.
Lars, Langemeyer, Christian, Ungermann
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