Results 241 to 250 of about 58,639 (259)

Regulation of ThermoTRP Channels by PIP2 and Cholesterol

2023
Transient receptor potential (TRP) ion channels are proteins that are expressed by diverse tissues and that play pivotal functions in physiology. These channels are polymodal and are activated by several stimuli. Among TRPs, some members of this family of channels respond to changes in ambient temperature and are known as thermoTRPs.
Tamara, Rosenbaum, Sara L, Morales-Lázaro   +1 more
openaire   +2 more sources

The multifaceted role of PIP2 in leukocyte biology

Cellular and Molecular Life Sciences, 2015
Phosphatidylinositol 4,5-bisphosphate (PIP2) represents about 1 % of plasma membrane phospholipids and behaves as a pleiotropic regulator of a striking number of fundamental cellular processes. In recent years, an increasing body of literature has highlighted an essential role of PIP2 in multiple aspects of leukocyte biology.
TUOSTO, Loretta, CAPUANO, CRISTINA, MUSCOLINI, MICHELA, SANTONI, Angela, GALANDRINI, Ricciarda   +4 more
openaire   +3 more sources

PIP2 and Talin Join Forces to Activate Integrin

The Journal of Physical Chemistry B, 2015
Integrins are major players in cell adhesion and migration, and malfunctions in controlling their activity are associated with various diseases. Nevertheless, the details of integrin activation are not completely understood, and the role of lipids in the process is largely unknown. Herein, we show using atomistic molecular dynamics simulations that the
Adam Orłowski, Sampo Kukkurainen, Annika Pöyry, Sami Rissanen, Ilpo Vattulainen, Vesa P. Hytönen, Tomasz Róg   +6 more
openaire   +3 more sources

PIP2 Phospholipid-Induced Aggregation of Tau Filaments Probed by Tip-Enhanced Raman Spectroscopy.

Angewandte Chemie, 2018
The morphology and secondary structure of peptide fibers formed by aggregation of tubulin-associated unit (Tau) fragments (K18), in the presence of the inner cytoplasmic membrane phosphatidylinositol component (PIP2 ) or heparin sodium (HS) as cofactors,
D. Talaga, Willy Smeralda, Laurie Lescos, Julien Hunel, Nad'a Lepejova-Caudy, C. Cullin, S. Bonhommeau, S. Lecomte   +7 more
semanticscholar   +1 more source

Binding of neomycin to phosphatidylinositol 4,5-biphosphate (PIP2)

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1989
Schacht (Schacht, J. (1976) J. Neurochem. 27, 1119-1124) demonstrated that neomycin, an aminoglycoside antibiotic, binds with high affinity to phosphatidylinositol 4,5-bisphosphate (PIP2). We investigated the binding of neomycin to PIP2 by making electrophoretic mobility measurements with multilamellar bilayer vesicles and surface potential ...
E, Gabev, J, Kasianowicz, T, Abbott, S, McLaughlin   +3 more
openaire   +2 more sources

???????????? ???????????????? ?????????????????? ???????? PIP2-???????????????????? ?? ?????????????? Sium latifolium (Apiaceae) ???? ???????? ?????????????? ?????????????? ????????????

2021
The dynamics of PIP-transcripts accumulation in S. latifolium leaves during twenty-four hours was demonstrated using RT-PCR method. Sium latifolium plants were sampled in nature in the Psyol River (aquatic plants) and on the riverside (terrestrial plants) near Velyka Bagachka settlement (Poltava Region, Ukraine).
openaire   +1 more source

Model predictions for PIP2 raft formation

Biophysical Journal, 2023
Zack Jarin, Richard M. Venable, Richard W. Pastor   +2 more
openaire   +1 more source

PIP2

2008
openaire   +2 more sources

PIP2 Controls Pain

Science Signaling, 2001
openaire   +1 more source

PIP2

2011
openaire   +1 more source