Results 51 to 60 of about 630,474 (269)

Off the Beaten Path: Let's Replace Term-Based Retrieval with k-NN Search

open access: yes, 2016
Retrieval pipelines commonly rely on a term-based search to obtain candidate records, which are subsequently re-ranked. Some candidates are missed by this approach, e.g., due to a vocabulary mismatch.
Andoni A.   +15 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Model establishment and solution of general product pipeline scheduling

open access: yesYou-qi chuyun, 2020
The technical patterns for unloading of oil products at various stations along product pipelines in China can be roughly divided into four types: continuous distribution, constant flow distribution, variable flow distribution and independent planning ...
Yamin YAN   +4 more
doaj   +1 more source

Load-store optimization for software pipelining

open access: yesACM SIGARCH Computer Architecture News, 2000
Software pipelining can generate efficient schedules for loop by overlapping the execution of operations from different iterations in order to exploit maximum Instruction Level Parallelism (ILP). Code optimization can decrease total number of calculations and memory related operations.
Dai, Min   +2 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Adaptability evaluation of the software for transient process simulation of supercritical CO2 pipelines

open access: yesYou-qi chuyun
Objective Transient processes like leakage and commissioning in CO2 pipeline operation pose simulation challenges due to the unique physical properties and phase behavior of CO2.
Xinyuan MA   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline

open access: yesBMC Bioinformatics, 2010
Background Next-generation amplicon sequencing enables high-throughput genetic diagnostics, sequencing multiple genes in several patients together in one sequencing run.
Deforce Dieter   +11 more
doaj   +1 more source

System Analysis of Pipeline Software - a Case Study of the Imaging Survey at ESO [PDF]

open access: yesJournal of Astronomy and Space Sciences, 2003
There are common features, in both imaging surveys and image processing, between astronomical observations and remote sensing. Handling large amounts of data, in an easy and fast way, has become a common issue.
Young-Soo Kim
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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