Results 101 to 110 of about 6,372 (199)

Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria

open access: yesBMC Medicine
Background The combination antimalarial artefenomel-piperaquine failed to achieve target efficacy in a phase 2b study in Africa and Vietnam. We retrospectively evaluated whether characterizing the pharmacological interaction of this antimalarial ...
Azrin N. Abd-Rahman   +14 more
doaj   +1 more source

Population Pharmacokinetics of Piperaquine after Two Different Treatment Regimens with Dihydroartemisinin-Piperaquine in Patients with Plasmodium falciparum Malaria in Thailand.

open access: yes, 2008
The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-piperaquine were characterized.
McGready, R   +13 more
core   +1 more source

The World Bank: false financial and statistical accounts and medical malpractice in malaria treatment.

open access: yes, 2006
and is the largest organisation operating with a mission to reduce poverty worldwide. Malaria destroys about 1 million lives a year; the disease is the leading parasitic cause of death for Africa’s children and impoverishment for their families.
Sibley, CH   +55 more
core   +1 more source

Simultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP.

open access: yes, 2002
For differential identification of sibling species in the Anopheles gambiae Giles complex (Diptera: Culicidae), including simultaneous separation of M and S molecular forms within An. gambiae Giles sensu stricto, we describe a PCR-RFLP method.
SANTOLAMAZZA, FEDERICA   +9 more
core   +1 more source

A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.

open access: yes, 2008
We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two different ...
Ngamije, D.   +17 more
core   +1 more source

The Plasmepsin-Piperaquine Paradox Persists

open access: yes
Abstract Malaria is still a major health issue in many parts of the world, particularly in tropical and subtropical regions of Africa, Asia, and Latin America. Despite significant efforts to control and eliminate the disease, malaria remains a leading cause of illness and death, mainly due to the occurrence of drug ...
Breanna Walsh   +3 more
openaire   +1 more source

Impact of Dolutegravir-, Lopinavir/Ritonavir-, and Efavirenz-Based Antiretrovirals on Piperaquine Pharmacokinetics in Ugandan Children Living with HIV. [PDF]

open access: yesClin Pharmacol Ther
Kajubi R   +26 more
europepmc   +1 more source

Efficacy of dihydroartemisinin-piperaquine to prevent malaria and complication-related malaria during pregnancy compared to sulfadoxine-pyrimethamine: a systematic review, meta-analysis, and meta-regression. [PDF]

open access: yesEpidemiol Infect
Simanjuntak AMT   +9 more
europepmc   +1 more source

Dissemination of EFFORT trial results in Indonesia: a stakeholder meeting report on tafenoquine and primaquine for radical cure of Plasmodium vivax. [PDF]

open access: yesMalar J
Pasaribu AP   +38 more
europepmc   +1 more source

Effects of malaria intermittent preventive treatment with dihydroartemisinin-piperaquine on antiretroviral drug concentrations in African pregnant women living with HIV. [PDF]

open access: yesAntimicrob Agents Chemother
Stöger L   +27 more
europepmc   +1 more source

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