Results 101 to 110 of about 6,372 (199)
Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage Plasmodium falciparum to predict efficacy in patients with malaria
BMC MedicineBackground The combination antimalarial artefenomel-piperaquine failed to achieve target efficacy in a phase 2b study in Africa and Vietnam. We retrospectively evaluated whether characterizing the pharmacological interaction of this antimalarial ...Azrin N. Abd-Rahman, Daniel Kaschek, Anne Kümmel, Rebecca Webster, Adam J. Potter, Anand Odedra, Stephen D. Woolley, Stacey Llewellyn, Lachlan Webb, Louise Marquart, Stephan Chalon, Myriam El Gaaloul, James S. McCarthy, Jörg J. Möhrle, Bridget E. Barber +14 moredoaj +1 more sourcePopulation Pharmacokinetics of Piperaquine after Two Different Treatment Regimens with Dihydroartemisinin-Piperaquine in Patients with Plasmodium falciparum Malaria in Thailand.
, 2008 The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-piperaquine were characterized.McGready, R, Phaiphun, L, Ashton, M, Ashley, E A, Ashley, EA, Stepniewska, K, Day, Nicholas, Mcgready, Rose, Lindegardh, N, Tarning, J, White, Nicholas, Nosten, F, White, N J, Day, N P J +13 morecore +1 more sourceThe World Bank: false financial and statistical accounts and medical malpractice in malaria treatment.
, 2006 and is the largest organisation operating with a mission to reduce poverty worldwide. Malaria destroys about 1 million lives a year; the disease is the leading parasitic cause of death for Africa’s children and impoverishment for their families.Sibley, CH, Mutabingwa, Theonest K., d'Alessandro, U, Watkins, WM, Fanello, CI, Garett, L., Talisuna, A., Attaran, Amir, D'Alessandro, U., Mutabingwa, TK, d'Alessandro, Umberto, Fanello, Caterina I, Sibley, Carol Hopkins, Barnes, K. I., Hopkins Sibley, C., Attaran, A, Roger Bate, Garrett, Laurie, Carol Hopkins Sibley, Bate, R, William M Watkins, Laurie Garrett, Watkins, William M., Watkins, William M, Fanello, C. I., Roberts, D, Amir Attaran, Garrett, L, Barnes, KI, d' Alessandro, Umberto, Barnes, Karen I., Ambrose Talisuna, Mutabingwa, Theonest K, Bate, Roger, Donald Roberts, Talisuna, Ambrose, Fanello, Caterina, Watkins, W. M., Jean-pierre Van Geertruyden, Van Geertruyden, J. P., Karen I Barnes, Theonest K Mutabingwa, Mutabingwa, T. K., Van Geertruyden, JP, Barnes, Karen I, Talisuna, A, Fred Binka, Roberts, D., Binka, Fred, Binka, F, Binka, F., Van Geertruyden, Jean-Pierre, Roberts, Donald, Attaran, A., Caterina I Fanello, Bate, R. +55 morecore +1 more sourceSimultaneous identification of species and molecular forms of the Anopheles gambiae complex by PCR-RFLP.
, 2002 For differential identification of sibling species in the Anopheles gambiae Giles complex (Diptera: Culicidae), including simultaneous separation of M and S molecular forms within An. gambiae Giles sensu stricto, we describe a PCR-RFLP method.SANTOLAMAZZA, FEDERICA, della Torre, A, A. Della Torre, DELLA TORRE, Alessandra, F. Santolamazza, Fanello, C, FANELLO C, C. Fanello, Fanello, Caterina, Santolamazza, F +9 morecore +1 more sourceA randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.
, 2008 We tested the efficacy and safety of chlorproguanil/dapsone co-administered with artesunate (CD+A) for the treatment of uncomplicated Plasmodium falciparum malaria in children compared with amodiaquine+sulfadoxine/pyrimethamine (AQ+SP) at two different ...Ngamije, D., D'Alessandro, U., Ngamije, D, Fanello, C. I., Karema, C., Van Doren, W., Ndahindwa, V, Uwimana, A, Van Overmeir, C, Uwimana, A., Fanello, CI, Van Doren, W, Van Overmeir, C., Ndahindwa, V., D'Alessandro, U, Curtis, J., Karema, C, Curtis, J +17 morecore +1 more sourceThe Plasmepsin-Piperaquine Paradox Persists
Abstract Malaria is still a major health issue in many parts of the world, particularly in tropical and subtropical regions of Africa, Asia, and Latin America. Despite significant efforts to control and eliminate the disease, malaria remains a leading cause of illness and death, mainly due to the occurrence of drug ...Breanna Walsh, Robert L Summers, Dyann F Wirth, Selina Bopp +3 moreopenaire +1 more sourceImpact of Dolutegravir-, Lopinavir/Ritonavir-, and Efavirenz-Based Antiretrovirals on Piperaquine Pharmacokinetics in Ugandan Children Living with HIV. [PDF]
Clin Pharmacol TherKajubi R, Koire M, Whalen ME, Orukan F, Okiring J, Marzan F, Richards K, Lier AJ, Goodwin J, Colt M, Pham X, He S, Chu DHT, Opira B, Kisitu GP, Sekabira R, Kekitiinwa A, Huynh D, Khoury M, Gallison K, Fotaki N, Mwima MW, Kamya MR, Aweeka FT, Parikh S, Huang L, Mwebaza N. +26 moreeuropepmc +1 more sourceEfficacy of dihydroartemisinin-piperaquine to prevent malaria and complication-related malaria during pregnancy compared to sulfadoxine-pyrimethamine: a systematic review, meta-analysis, and meta-regression. [PDF]
Epidemiol InfectSimanjuntak AMT, Wijayanto FPS, Nugraha RTH, Prathama FH, Ramadhan RN, Mulya Perdana T, Haposan JH, Nugrahani AD, Hartantri Y, Maulana S. +9 moreeuropepmc +1 more sourceDissemination of EFFORT trial results in Indonesia: a stakeholder meeting report on tafenoquine and primaquine for radical cure of Plasmodium vivax. [PDF]
Malar JPasaribu AP, Jimanto V, Ainur F, Saragih NR, Hadi H, Siagian DSP, Sinaga BJ, Satyagraha AW, Laihad FJ, Diptyanusa A, Ubra RR, Tekege O, Darmayanti L, Herdiana H, Adella J, Mannion K, Curry E, Poespoprodjo JR, Kenangalem E, Burdam FH, Sutanto I, Nelwan EJ, Ganadhi GJ, Shrestha B, Mnjala H, Hawley WA, Prameswari HD, Theodora M, Silalahi FSM, Susanto H, Immanuella F, Puspadewi RT, Fajariyani SB, Samad I, Supriyanto D, Muhafilah N, Isa R, Price RN, Thriemer K. +38 moreeuropepmc +1 more sourceEffects of malaria intermittent preventive treatment with dihydroartemisinin-piperaquine on antiretroviral drug concentrations in African pregnant women living with HIV. [PDF]
Antimicrob Agents ChemotherStöger L, Mischlinger J, Nhampossa T, Mombo-Ngoma G, Esen M, Tchouatieu A-M, Brunet M, Mendes A, Dimessa Mbadinga LB, Gamberini S, Ndzebe Ndoumba W, Figueroa-Romero A, Lell B, Lagler H, Zoleko-Manego R, El Gaaloul M, Méndez S, Botella N, Sanz S, Piqueras M, Sevene E, Saúte F, Wicha SG, Soy D, Menéndez C, Ramharter M, González R, MAMAH Study Group. +27 moreeuropepmc +1 more source