Results 91 to 100 of about 6,372 (199)

Final parameter estimates describing piperaquine population pharmacokinetics.

, 2017
Final parameter estimates describing piperaquine population pharmacokinetics.
Michael D. Edstein (1846186), Prabin Dahal (3628118), Lesley Workman (368956), Khin Maung Lwin (171017), Leah Mwai (181144), Richard M. Hoglund (3628115), Nguyen Xuan Thanh (3628109), Nancy C. Sambol (2793025), Sunil Parikh (370188), Jean Bosco Ouedraogo (3628121), Steffen Borrmann (4910), Elizabeth A. Ashley (237173), Francois Nosten (2580787), Nguyen Ngoc Quang (3628112), Philippe J. Guerin (137002), Nicholas J. White (35779), Ric N. Price (35538), Joel Tarning (387123), Christian Nsanzabana (342692), Issaka Zongo (86854), Nicholas P. J. Day (35781), Karen I. Barnes (265208), Aung Pyae Phyo (232872), Rose McGready (17231)   +23 more
core   +1 more source

The effect of dosing regimens on the antimalarial efficacy of dihydroartemisinin-piperaquine: a pooled analysis of individual patient data.

PLoS Medicine, 2013
BackgroundDihydroartemisinin-piperaquine (DP) is increasingly recommended for antimalarial treatment in many endemic countries; however, concerns have been raised over its potential under dosing in young children.
WorldWide Antimalarial Resistance Network (WWARN) DP Study Group
doaj   +1 more source

Artenimol–piperaquine in children with uncomplicated imported falciparum malaria: experience from a prospective cohort

Malaria Journal, 2019
Background Although malaria remains one of the major public health threats in inter-tropical areas, there is limited understanding of imported malaria in children by paediatricians and emergency practitioners in non-endemic countries, often resulting in ...
Lauren Pull, Jean-Marc Lupoglazoff, Matthew Beardmore, Jean-François Michel, Pierre Buffet, Olivier Bouchaud, Jean-Yves Siriez   +6 more
doaj   +1 more source

A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype–genotype association study [PDF]

, 2016
International audienceBACKGROUND:Western Cambodia is the epicentre of Plasmodium falciparum multidrug resistance and is facing high rates of dihydroartemisinin-piperaquine treatment failures.
Ke, Sopheakvatey, Saintpierre, Benjamin, Huy, Rekol, Ross, Leila S, Nuel, Grégory, Witkowski, Benoit, Ma, Laurence, Eam, Rotha, Duru, Valentine, Ariey, Frédéric, Chy, Sophy, Leang, Rithea, Mercereau-Puijalon, Odile, Legrand, Eric, Ken, Malen, Bouillon, Anthony, Beghain, Johann, Loch, Kaknika, Ringwald, Pascal, Domergue, Anais, Khim, Nimol, Barale, Jean-Christophe, Khean, Chanra, Kim, Saorin, Ménard, Didier, Bouchier, Christiane, Kloeung, Nimol, Fidock, David A   +27 more
core   +1 more source

A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia. [PDF]

, 2007
OBJECTIVES: To compare the efficacy and tolerability of dihydroartemisinin-piperaquine (DHA-PQP) with that of a 3-day regimen of mefloquine and artesunate (MAS3) for the treatment of uncomplicated falciparum malaria in Cambodia.
D. Socheat, Van Herp, M, Nong, S, Goubert, L, Ashley, E A, M. Van Herp, S. Nong, E. A. Ashley, Brockman, A., Uong, S, L. Goubert, Goubert, L., Socheat, D, Van Damme, W., W. Van Damme, Chan, S, Van Herp, M., Uong, S., B. Janssens, S. Chan, A. Brockman, Van Damme, W, Socheat, D., Brockman, A, Ashley, E. A., S. Uong, Janssens, B., Janssens, B, Chan, S.   +28 more
core   +1 more source

High therapeutic efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Somalia

Malaria Journal, 2019
Background Artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DHA/PPQ) are the recommended first- and second-line treatments, respectively, for uncomplicated falciparum malaria in Somalia.
Marian Warsame, Abdillahi Mohamed Hassan, Abdikarim Hussein Hassan, Ali Mohamed Jibril, Nimol Khim, Abdulkadir Mohamed Arale, Ahamed Hassan Gomey, Zainab Said Nur, Said Mohamed Osman, Marian Said Mohamed, Ali Abdulrahman, Fahmi Essa Yusuf, Jamal Ghilan Hefzullah Amran, Benoit Witkowski, Pascal Ringwald   +14 more
doaj   +1 more source

Malaria diagnosis under field conditions in the Venezuelan Amazon.

, 2008
To improve practical, accurate diagnosis of malaria in the Amazon rainforest of Venezuela, two rapid diagnostic tests (RDT) (OptiMAL-IT) and FalciVax) and a laboratory light microscope, used in the field with a battery-operated head lamp as an external ...
Fanello, C. I., Metzger, W. G., Magris, M., Gonçalves, J., Rodriguez, I., Bongard, Emily, Vivas, L., Gonçalves, J, Fanello, CI, Metzger, WG, Rodriguez, I, Vivas, L, Vivas-Martínez, S, Bongard, E, Magris, M, Vivas-Martínez, S.   +15 more
core   +1 more source

Decreased dihydroartemisinin-piperaquine protection against recurrent malaria associated with Plasmodium falciparum plasmepsin 3 copy number variation in Africa

Nature Communications
Dihydroartemisinin-piperaquine (DHA-PPQ) is being recommended in Africa for the management of uncomplicated Plasmodium falciparum malaria and for chemoprevention strategies, based on the ability of piperaquine to delay re-infections. Although therapeutic
Leyre Pernaute-Lau, Mario Recker, Mamadou Tékété, Tais Nóbrega de Sousa, Aliou Traore, Bakary Fofana, Kassim Sanogo, Ulrika Morris, Juliana Inoue, Pedro E. Ferreira, Nouhoum Diallo, Jürgen Burhenne, Issaka Sagara, Alassane Dicko, Maria I. Veiga, Walter Haefeli, Anders Björkman, Abdoulaye A. Djimde, Steffen Borrmann, José Pedro Gil   +19 more
doaj   +1 more source

Therapeutic Efficacy and Safety of Dihydroartemisinin-Piperaquine (DP) for the Treatment of Uncomplicated Plasmodium Vivax Malaria: A Single Center Study

JLUMHS, 2017
BACKGROUND: Ninety-five millions of Pakistan's 161 million people, roughly 60% of Pakistan’s population live in malaria endemic regions. Despite a well-established malaria control programme, 500,000 malaria infections and 50,000 malaria-attributable ...
Salma Shaikh, Imran Ahmed, Sikander Munir Memon , Abdul Saleem, Hafeezullah Memon, Ayaz Babar   +5 more
doaj   +1 more source

Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study.

PLoS ONE, 2016
BackgroundThe combination of short-acting dihydroartemisinin and long-acting piperaquine (DP) is among the first-line therapies for the treatment of uncomplicated Plasmodium falciparum malaria.
Nancy C Sambol, Jordan W Tappero, Emmanuel Arinaitwe, Sunil Parikh   +3 more
doaj   +1 more source