Results 71 to 80 of about 6,372 (199)

Drug-Resistant Polymorphisms and Copy Numbers in Plasmodium falciparum, Mozambique, 2015

Emerging Infectious Diseases, 2018
One of the fundamental steps toward malaria control is the use of antimalarial drugs. The success of antimalarial treatment can be affected by the presence of drug-resistant populations of Plasmodium falciparum.
Himanshu Gupta, Eusebio Macete, Helder Bulo, Crizolgo Salvador, Marian Warsame, Eva Carvalho, Didier Ménard, Pascal Ringwald, Quique Bassat, Sonia Enosse, Alfredo Mayor   +10 more
doaj   +1 more source

Evaluation of a sticky trap for collecting Aedes (Stegomyia) adults in a dengue-endemic area in Thailand. [PDF]

, 2008
Development of new operational techniques for collection and monitoring of adult Stegomyia mosquitoes is considered a pressing need for surveillance and prevention of arboviruses.
Valerio, Laura, Jones, JW, Facchinelli, Luca, Scott, Thomas W, Koenraadt, CJ, Kijchalao, U, della Torre, A, Koenraadt, Constantianus JM, Jones, James W, Valerio, L, Scott, TW, Facchinelli, L, Fanello, C, della Torre, Alessandra, Fanello, Caterina, Kijchalao, Udom   +15 more
core   +1 more source

Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine

Malaria Journal, 2010
Background Previous efforts to eradicate malaria parasites, particularly Plasmodium falciparum, have failed in part due to the emergence of drug resistant parasites and mosquitoes resistant to insecticides. Using an artemisinin-based combination therapy (
Seila Suon, Sokunthea Sreng, Deng Changsheng, Dara Prak, Tan Bo, Socheat Duong, Song Jianping, Ou Fengzhen, Jian Huaxiang, Li Guoqiao   +9 more
doaj   +1 more source

The Epidemiology of Sickle Cell Disease in Sub‐Saharan Africa: Current Knowledge and Gaps to be Filled

American Journal of Hematology, Volume 101, Issue S1, Page 5-16, April 2026.
What are the available data on incidence & prevalence prognosis risk factors of severity of sickle cell disease in sub‐Saharan Africa? ABSTRACT Sickle Cell Disease (SCD) is highly prevalent in sub‐Saharan Africa. Epidemiological data remain sparse, but regional screening and research initiatives are expanding.
Brigitte Ranque, Leon Tshilolo, Thomas N. Williams   +2 more
wiley   +1 more source

Efficacy of antimalarial drugs for treatment of uncomplicated falciparum malaria in Asian region: A network meta-analysis.

PLoS ONE, 2019
BackgroundThe WHO recommends artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated falciparum malaria. Hence, monitoring the efficacy of antimalarial drugs is a key component of malaria control and elimination.
Cho Naing, Maxine A Whittaker, Norah Htet Htet, Saint Nway Aye, Joon Wah Mak   +4 more
doaj   +1 more source

Electrocardiographic safety evaluation of dihydroartemisinin piperaquine in the treatment of uncomplicated falciparum malaria. [PDF]

, 2007
Dihydroartemisinin-piperaquine (DP) could become a leading fixed combination malaria treatment worldwide. Although there is accumulating evidence of efficacy and safety from clinical trials, data on cardiotoxicity are limited.
Singhasivanon, P, Price, R N, Peto, L, Mytton, O T, La, Y, Ashley, E A, Ashley, EA, Hae, R, Mytton, OT, Price, RN, White, NJ, White, Nicholas, Nosten, F, White, N J   +13 more
core  

Malaria in Bangladesh, 2000–2025: Navigating the Headwinds From Control to Elimination

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Bangladesh has dramatically reduced its malaria burden since 2000, confining the disease to specific geographic zones. However, the national 2030 elimination goal is now threatened by a complex interplay of biological, ecological, and social factors.
Abdullaha Al Mamun, Mustafa Sarwar A. Kayenat, K. A. M. Inzamul Islam   +2 more
wiley   +1 more source

Artemisinin‐Based Combination Therapies in East Africa: A Systematic Review of Quality, Clinical Efficacy, and Regulatory Progress Towards Sustainable Malaria Control

Tropical Medicine &International Health, Volume 31, Issue 3, Page 254-273, March 2026.
ABSTRACT Background Malaria is a major public health issue in East Africa, leading to widespread illness and fatalities, especially among vulnerable populations such as children under 5 years of age and pregnant women. Artemisinin‐based combination therapies (ACTs) are the primary treatment modality; however, their efficacy is undermined by the ...
Yesuneh Tefera Mekasha, Addisu Afrassa Tegegne, Tapfumanei Mashe, Million Girma, Gemmechu Hasen, Sileshi Belew   +5 more
wiley   +1 more source

Piperaquine Population Pharmacokinetics and Cardiac Safety in Cambodia [PDF]

Antimicrobial Agents and Chemotherapy, 2017
ABSTRACTDespite the rising rates of resistance to dihydroartemisinin-piperaquine (DP), DP remains a first-line therapy for uncomplicated malaria in many parts of Cambodia. While DP is generally well tolerated as a 3-day DP (3DP) regimen, compressed 2-day DP (2DP) regimens were associated with treatment-limiting cardiac repolarization effects in a ...
Pattaraporn, Vanachayangkul, Chanthap, Lon, Michele, Spring, Sommethy, Sok, Winita, Ta-Aksorn, Chanikarn, Kodchakorn, Sut-Thang, Pann, Soklyda, Chann, Mali, Ittiverakul, Sabaithip, Sriwichai, Nillawan, Buathong, Worachet, Kuntawunginn, Mary, So, Theng, Youdaline, Erin, Milner, Mariusz, Wojnarski, Charlotte, Lanteri, Jessica, Manning, Satharath, Prom, Mark, Haigney, Louis, Cantilena, David, Saunders   +21 more
openaire   +2 more sources

Exploration of Antiplasmodium Chemical Space Identifies New Inhibitors of β‐Hematin Formation from Areas of Enrichment

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
An enrichment map, developed using principal components analysis (PCA), shows the relative abundance of inhibitors of synthetic hemozoin (β‐hematin) formation in antiplasmodium chemical space. This 2‐dimensional landscape can be mined to unearth new chemotypes for antimalarial drug development.
Jessica L. Thibaud, Dirkie C. Myburgh, Rebecca D. Sandlin, Kim Y. Fong, Larnelle F. Garnie, Kathryn J. Wicht, David Kuter, David W. Wright, Timothy J. Egan, Katherine A. de Villiers   +9 more
wiley   +1 more source