Results 11 to 20 of about 73,428 (238)

Defining stage-specific activity of potent new inhibitors of Cryptosporidium parvum growth in vitro [PDF]

, 2020
Currently, nitazoxanide is the only FDA-approved treatment for cryptosporidiosis; unfortunately, it is ineffective in immunocompromised patients, has varied efficacy in immunocompetent individuals, and is not approved in infants under 1 year of age ...
Funkhouser-Jones, Lisa J, Ravindran, Soumya, Sibley, L. David   +2 more
core   +2 more sources

Development of a targeted GC/MS screening method and validation of an HPLC/DAD quantification method for piperazines–amphetamines mixtures in seized material

Egyptian Journal of Forensic Sciences, 2014
Piperazine-related drugs are sold as party pills in the form of tablets, capsules, liquids or powders. These party pills can contain several piperazine derivatives, or even a mixture of piperazines and amphetamine derivatives.
Yacine Boumrah, Martine Rosset, Yannick Lecompte, Sabrina Bouanani, Kamel Khimeche, Abdellah Dahmani   +5 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of the hydrochloride salt of 8-{4-[(6-phenylpyridin-3-yl)methyl]piperazin-1-yl}-3,4-dihydroquinolin-2(1H)-one

Acta Crystallographica Section E: Crystallographic Communications, 2021
The amine 8-{4-[(6-phenylpyridin-3-yl)methyl]piperazin-1-yl}-3,4-dihydroquinolin-2(1H)-one was crystallized as the hydrochloride salt, 4-(2-oxo-1,2,3,4-tetrahydroquinolin-8-yl)-1-[(6-phenylpyridin-3-yl)methyl]piperazin-1-ium chloride, C25H27N4+·Cl− (I ...
Nisar Ullah, Helen Stoeckli-Evans
doaj   +1 more source

Piperazine Hepatitis

Gastroenterology, 1976
The first reported case of piperazine toxicity resembling viral hepatitis is described in a 25-year-old woman. The illness, which was severe, occurred after administration of the drug on two separate occasions. The evidence favors a hypersensitivity mechanism rather than a direct toxic effect of piperazine or its metabolites on the liver.
A N, Hamlyn, J S, Morris, I, Sarkany, S, Sherlock   +3 more
openaire   +2 more sources

Poly(amidoamine)s synthesis, characterisation and interaction with BSA [PDF]

, 2014
Cationic poly(amidoamine)s (PAAs) were synthesised and characterised by NMR and gel permeation chromatography. Their thermal properties were investigated using thermogravimetric analysis and differential scanning calorimetry.
Akinc, Almeida, Anand, Antonov, Boeris, Boeris, Brostow, Bujacz, Coué, Danusso, Deep, Dey, Dhalluin, Ferruti, Ferruti, Ferruti, Funhoff, Giancola, Gill, Gu, Julie L. N. Dubois, Kalogeras, Karayianni, Kishimura, Lakowicz, Lavignac, Lavignac, Lavignac, Leader, Liu, Luo, Nathalie Lavignac, Piest, Plesner, Prevette, Ranucci, Richardson, Richardson, Romanini, Seyrek, Tanzi, Torchilin, van der Aa, Vlasova, von Harpe, Won   +45 more
core   +1 more source

Syntheses and crystal structures of 4-(4-nitrophenyl)piperazin-1-ium benzoate monohydrate and 4-(4-nitrophenyl)piperazin-1-ium 2-carboxy-4,6-dinitrophenolate

Acta Crystallographica Section E: Crystallographic Communications, 2022
Crystal structures are reported for two molecular salts containing the 4-(4-nitrophenyl)piperazin-1-ium cation. Co-crystallization from methanol/ethyl acetate solution of N-(4-nitrophenyl)piperazine with benzoic acid gives the benzoate salt, which ...
Holehundi J. Shankara Prasad, Devaraju, Vinaya, Hemmige S. Yathirajan, Sean R. Parkin, Christopher Glidewell   +5 more
doaj   +1 more source

Copper(II) Complexes with Tetradentate Piperazine-Based Ligands: DNA Cleavage and Cytotoxicity

Inorganics, 2021
Five-coordinate Cu(II) complexes, [Cu(Ln)X]ClO4/PF6, where Ln = piperazine ligands bearing two pyridyl arms and X = ClO4− for Ln = L1 (1-ClO4), L2 (2-ClO4), L3 (3-ClO4), and L6 (6-ClO4) as well as [Cu(Ln)Cl]PF6 for Ln = L1 (1-Cl), L4 (4-Cl), and L5 (5-Cl)
Sebastian Doniz Kettenmann, Yvonne Nossol, Febee R. Louka, Julia R. Legrande, Elise Marine, Roland C. Fischer, Franz A. Mautner, Vinja Hergl, Nora Kulak, Salah S. Massoud   +9 more
doaj   +1 more source

Six 1-aroyl-4-(4-methoxyphenyl)piperazines: similar molecular structures but different patterns of supramolecular assembly

Acta Crystallographica Section E: Crystallographic Communications, 2019
Six new 1-aroyl-4-(4-methoxyphenyl)piperazines have been prepared, using coupling reactions between benzoic acids and N-(4-methoxyphenyl)piperazine.
Haruvegowda Kiran Kumar, Hemmige S. Yathirajan, Belakavadi K. Sagar, Sabine Foro, Christopher Glidewell   +4 more
doaj   +1 more source

Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity

Pharmaceuticals, 2023
Benzimidazole anthelmintic drugs hold promise for repurposing as cancer treatments due to their interference with tubulin polymerization and depolymerization, manifesting anticancer properties.
Kameliya Anichina, Anelia Mavrova, Dimitar Vuchev, Galya Popova-Daskalova, Giada Bassi, Arianna Rossi, Monica Montesi, Silvia Panseri, Filip Fratev, Emilia Naydenova   +9 more
doaj   +1 more source

1,4-Bis(4-nitrosophenyl)piperazine: novel bridging ligand in dinuclear complexes of rhodium(III) and iridium(III). [PDF]

, 2012
The synthesis, spectroscopic characterization and crystal structures of the first 1,4-bis(4-nitrosophenyl)piperazine (BNPP) (4) bridged dinuclear complexes of rhodium(III) and iridium(III) are presented. The reaction of the μ2-halogenido-bridged dimers [(
Barth, Florian, Lorenz, Ingo-Peter, Wirth, Stefan   +2 more
core   +1 more source