Results 21 to 30 of about 37,749 (227)

Densities, Apparent Molar Volume, Expansivities, Hepler’s Constant, and Isobaric Thermal Expansion Coefficients of the Binary Mixtures of Piperazine with Water, Methanol, and Acetone at T = 293.15 to 328.15 K

International Journal of Chemical Engineering, 2018
The properties of 3 binary mixtures containing piperazine were investigated in this work. In a first step, the densities for the two binary mixtures (piperazine + methanol) and (piperazine + acetone) were measured in the temperature range of 293.15 to ...
Qazi Mohammed Omar, Jean-Noël Jaubert, Javeed A. Awan   +2 more
doaj   +1 more source

Metallocene-Naphthalimide Derivatives: The Effect of Geometry, DFT Methodology, and Transition Metals on Absorption Spectra

Molecules, 2023
In the present paper, the photophysical properties of metallocene-4-amino-1,8-naphthalimide-piperazine molecules (1-M2+), as well as their oxidized and protonated derivatives (1−M3+, 1-M2+-H+, and 1-M3+-H+), where M = Fe, Co, and Ni, were studied via DFT
Christina Eleftheria Tzeliou, Demeter Tzeli   +1 more
doaj   +1 more source

Rearrangement of Imidazolidine to Piperazine Rings in the Presence of Dy^III

Chemistry Proceedings, 2022
The formation of imidazolidines from secondary amines and aldehydes is well known. This small cycle can act as a nitrogen donor, and it is usually stable when it coordinates to metal ions.
Julio Corredoira-Vázquez, Paula Oreiro-Martínez, Ana M. García Deibe, Jesús Sanmartín-Matalobos, Matilde Fondo   +4 more
doaj   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

Angewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang, Bin Liu, Elise M. Ackerman, Yichen Xiang, Hung V.‐T. Nguyen, Yivan Jiang, Angela N. Koehler, Jeremiah A. Johnson   +7 more
wiley   +2 more sources

Recent research progress and outlook on the bioactivities and mechanism of piperazine pesticides

Journal of Integrative Agriculture
Piperazine is a nitrogen-containing heterocyclic compound that is commonly used as an intermediate linking group in the structural derivation of compounds.
Yanju Wang, Baoan Song
doaj   +1 more source

4-(4-Methylphenylsulfonyl)piperazin-1-ium trifluoroacetate

Acta Crystallographica Section E, 2013
In the title salt, C11H17N2O2S+·CF3COO−, the cation is protonated at the secondary piperazine N atom. The dihedral angle between the benzene ring and the piperazine mean plane is 85.54 (10)°.
S. Sreenivasa, N. R. Mohan, T. Madhu Chakrapani Rao, P. A. Suchetan, B. S. Palakshamurthy, Vijithkumar   +5 more
doaj   +1 more source

A Novel Class of “Super‐Strained” Spiro Heterocycles: Gateway to 1‐Azaspiro[3.3]heptane Derivatives, and Biological Validation

Angewandte Chemie, EarlyView.
A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho, Annarita Vicenti, Marco Colella, Francesco Pasca, Giuseppe Romanazzi, Mauro Niso, Carmen Abate, Ernesto Mesto, Emanuela Schingaro, Renzo Luisi   +9 more
wiley   +2 more sources

Strain‐Release Pentafluorosulfanylation of Carbonyl‐Containing Disubstituted Bicyclobutanes: A Fortuitous Path to SF5‐Containing Oxa[2.1.1]bicyclohexanes

Angewandte Chemie, EarlyView.
A regio‐ and diastereoselective method for strain‐release pentafluorosulfanylation of carbonyl‐containing 1,3‐disubstituted [1.1.0]bicyclobutanes (BCBs) was developed that led to several fortuitous discoveries. For instance, the resultant SF5‐cyclobutanes (SF5‐CBs) exhibit close SF5⋯C═X contacts (X = C, N, O) and provide synthetic access to a new class
Alexander M. Stephens, Jake Anthony Olvera, Yannick Kraemer, Tyson Vu, Wang‐Yeuk Kong, Sudiksha Chaturvedi, Jeffrey M. Wang, Lauren M. Holder, Dean J. Tantillo, Cody Ross Pitts   +9 more
wiley   +2 more sources

Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles

Angewandte Chemie, EarlyView.
Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley   +2 more sources

Substanţele psihoactive noi şi riscurile consumului la copii şi adolescenţi [PDF]

Romanian Journal of Pediatrics, 2019
Conform definiției stabilite de Monitorul European pentru Droguri şi Toxicomanie (European Monitoring Centre for Drugs and Drug Addiction – EMCDDA), o „substanță psihoactivă nouă este considerată orice substanță narcotică sau psihotropă în formă pură sau
Viorela Nițescu
doaj   +1 more source