Results 51 to 60 of about 73,428 (238)

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Crystal structure of 3-{[4-(2-methoxyphenyl)piperazin-1-yl]methyl}-5-(thiophen-2-yl)-1,3,4-oxadiazole-2(3H)-thione

Acta Crystallographica Section E: Crystallographic Communications, 2016
The title compound, C18H20N4O2S2, is a new 1,3,4-oxadiazole and a key pharmacophore of several biologically active agents. It is composed of a methyl(thiophen-2-yl)-1,3,4-oxadiazole-2(3H)-thione moiety linked to a 2-methoxyphenyl unit via a piperazine ...
Monirah A. Al-Alshaikh, Hatem A. Abuelizz, Ali A. El-Emam, Mohammed S. M. Abdelbaky, Santiago Garcia-Granda   +4 more
doaj   +1 more source

MODELING POLARIZATION CURVE IN AN AQUEOUS CARBONATED SOLUTION OF PIPERAZINE

Journal of Engineering and Sustainable Development, 2022
A polarization curve model is developed for carbon steel in an aqueous carbonated solution of piperazine (PZ). This model has been used to generate the polarization curve and control the parameters relevant to the corrosion rate of carbon steel in the PZ-
Lubna Ghalib, Brahim Si Ali, Shaukat Ali Mazari   +2 more
doaj   +1 more source

Supramolecular Complexation of \u3cem\u3eN\u3c/em\u3e-Alkyl- and \u3cem\u3eN\u3c/em\u3e,\u3cem\u3eN\u3c/em\u3e′-Dialkylpiperazines with Cucurbit[6]uril in Aqueous Solution and in the Solid State [PDF]

, 2009
Water seeds: Complex stoichiometry/composition and degree of oligomerization (oligomeric supramolecular complex formation) of cucurbit[6]uril (CB[6]) with N-alkyl- and N,N′-dialkylpiperazine were investigated in aqueous solutions by means of isothermal ...
Inoue, Yoshihisa, Kim, Kimoon, Ko, Young Ho, Lindeman, Sergey V., Mori, Tadashi, Rathore, Rajendra, Rekharsky, Mikhail V., Sato, Akihiro, Selvapalam, Narayanan, Shiba, Kouhei, Shiro, Motoo, Yamamura, Hatsuo   +11 more
core   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

Aminal‐linked Covalent Organic Frameworks for Light Energy Upconversion

Angewandte Chemie, EarlyView.
Aminal‐linked covalent organic frameworks incorporating anthracene units are introduced as solid‐state platforms for triplet–triplet annihilation upconversion. The crystalline materials retain chromophore electronic properties and exhibit fluorescence quantum yields of up to 40%.
Mateusz Brzeziński, Agata Tyszka‐Gumkowska, Aleksander Gorski, Marek J. Potrzebowski, Tomasz Polczyk, Wojciech Wegner, Sylwester Gawinkowski, Jakub Ostapko   +7 more
wiley   +2 more sources

Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]

, 1990
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Ahnert-Hilger, G., Dayanithi, G., Gratzl, Manfred, Nordmann, J. J., Weller, U.   +4 more
core   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Triple Matrix Confinement‐Induced Ultrabright Afterglow From Carbon Dots With Multivariate Responsive Afterglow Colors for Advanced Dynamic Information Encryption

Angewandte Chemie, EarlyView.
A novel carbon dots material (BUL‐CDs) with an initial afterglow brightness (406 cd m−2) far exceeding that of other afterglow luminescent materials was developed. Furthermore, the BUL‐CDs exhibited time‐dependent afterglow colors, excitation‐dependent afterglow colors, and thermochromic afterglow in response to triplet variables.
Yupeng Liu, Yiming Hao, Yi Li, Xiaofan Xia, Xichang Ou, Xue Wu, Jun Wu, Ruifeng Zheng, Dongbo Guo, Shi Chen, Jing Li, Jinyang Zhu, Qijun Li, Songnan Qu   +13 more
wiley   +2 more sources