Results 71 to 80 of about 45,771 (255)

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Crystal structure of 7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-2H-chromen-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the title compound, C15H18N2O3, the coumarin ring is essentially planar, with an r.m.s. deviation of 0.012 Å. An intramolecular O—H...N hydrogen bond forms an S(6) ring motif. The piperazine ring adopts a chair conformation.
Koji Kubono, Ryuma Kise, Yukiyasu Kashiwagi, Keita Tani, Kunihiko Yokoi   +4 more
doaj   +1 more source

Stable Zr-Piperazine MOFs for Efficient Gold Recovery

Gold's importance in various industries, the ever-rising demand of electronics and shrinking gold reserves all underscore the pressing need to develop effective gold recovery methods from waste.
Belin, Anne Faustine Sido, Roth, Jocelyn Richard, Meoli, Matthieu, Scopelliti, Rosario, Queen, Wendy Lee, Stoian, Dragos   +5 more
core   +1 more source

Rationalizing Product Formation in Piperazine Degradation: A Computational Study

, 2021
Knowledge of the origins of degradation products observed during amine degradation is crucial to developing new, more efficient amines for future carbon-capture plants.
Christopher Parks (6988787), Kevin Hughes, Christopher Parks, Mohamed Pourkashanian, Kevin Hughes (1776676), Mohamed Pourkashanian (1808431)   +5 more
core   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Reaction of piperazine with trimethylacetic arylcarboxylic anhydride; A convenient method for preparing monoacylated piperazine derivatives 

, 2020
[[abstract]]A series of monosubstituted piperazine derivatives were obtained by the reaction of piperazine with trimethylacetic arylcarboxylic anhydrides in good yields, which were prepared in situ from arylcarboxylic acid with trimethylacetyl chloride ...
Luh, BJ, 陸寶珍 
core   +2 more sources

Antihelminic Activity of Carvacrol, Thymol, Cinnamaldehyde and P-Cymen Against the Free-Living Nematode Caenorhabditis elegans and Rat Pinworm Syphacia muris

Acta Veterinaria, 2018
In the present study we tested the dose andh time dependence of the antinematodal effects of carvacrol and tyhmol on Caenorabditis elegans, and the efficacy of carvacrol, thymol, p-cymene and cinnamaldehyde,which were administrated in the drinking water ...
Marjanović S. Đorđe, Bogunović Danica, Milovanović Mirjana, Marinković Darko, Zdravković Nemanja, Magaš Vladimir, Trailović M. Saša   +6 more
doaj   +1 more source

The crystal structure of 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine: a three-dimensional hydrogen-bonded framework, augmented by π–π stacking interactions and I...N halogen bonds

Acta Crystallographica Section E: Crystallographic Communications, 2019
In 1-(2-iodobenzoyl)-4-(pyrimidin-2-yl)piperazine, C15H15IN4O, the central piperazine ring adopts an almost perfect chair conformation with the pyrimidine substituent in an equatorial site.
Ninganayaka Mahesha, Hemmige S. Yathirajan, Tetsundo Furuya, Takashiro Akitsu, Christopher Glidewell   +4 more
doaj   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

1,4-Bis(2-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)piperazine

Molbank
The reaction of (−)-nopol mesylate with piperazine in acetonitrile under reflux, afforded symmetric 1,4-bis(2-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethyl)piperazine in a good yield.
Nikolai S. Li-Zhulanov, Artem D. Rogachev, Yuri V. Gatilov, Konstantin P. Volcho, Nariman F. Salakhutdinov   +4 more
doaj   +1 more source